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dotB from Legionella pneumophila str. Lens

Victor ID 1462
Gene Name dotB from Legionella pneumophila str. Lens
Sequence Strain (Species/Organism) Legionella pneumophila str. Lens
NCBI Gene ID 3114737
NCBI Protein GI 54295516
Locus Tag lpl2603
Protein Accession YP_127931.1
Other Database IDs UniProtKB-ID: Q5WTC2_LEGPL
UniRef100: UniRef100_Q5ZS43
UniRef90: UniRef90_Q5ZS43
UniRef50: UniRef50_Q5ZS43
UniParc: UPI00000B484B
EMBL: CR628337
EMBL-CDS: CAH16844.1
RefSeq_NT: NC_006369.1
GenomeReviews: CR628337_GR
KEGG: lpf:lpl2603
LegioList: lpl2603
eggNOG: COG2805
HOGENOM: HBG757455
OMA: IISERVY
ProtClustDB: CLSK914927
BioCyc: LPNE297245:LPL2603-MONOMER
Taxonomy ID 297245
Gene Starting Position 2969518
Gene Ending Position 2970651
Gene Strand (Orientation) +
Protein Name defect in organelle trafficking protein DotB (ATPase)
DNA Sequence
>gi|54292964:2969518-2970651 Legionella pneumophila str. Lens, complete genome
AATGTCTATGGATAATATTAATTTAATGCCCGATGAGCCAACTCGTTTCACTCCAGTATTCATGGACAGA
ATGCTGGAGCATGCAGAAAGCCTGAATGCTTCAGATATAACAATCCAAACTGGCGAACCCATTTTTGCAG
AGGTTTATGGAAGACTCCTTAAAATTACAAATCGACGTCTTTCCAATACAGAATTGGGCGACCTTATAAA
TTCCATTTATGGCCCGAATGCCACGACACAATTACTTTCCGGTAAAGATATAGATACTCATTATGAGTTT
CGGCCCAACCGTGGTGTACGCTATCGATATAGGGTTAACGCGACTGCCTGCCTGGTAGAAGGTCATGATG
CCATTCAGATCACATTAAGAACTATTCCGACCACACCACCCAAACTCAGTACCATGAACCTCCCTGATAA
CATTATTGAAGCGATTGCTCCACAGGAAGGAATCGTGTTTATCACAGGCGCTACCGGTTCGGGCAAATCG
ACATTGTTGGCGTCCATTATTCGAGAGCTTATTGAAACATCAGACTCAAACCGCAAAGTATTAACTTACG
AATCCCCAATAGAATTCGTCTATGATGAAATTGAAACAATTTCCGCTGTAGTAAGCCAATCAGAGATTCC
AAGACACTTACCCAACTTTGCTGATGGAGTAAGAAACGCATTAAGACGAAAGCCGAGATTAATTATGGTG
GGTGAATGTCGTGATGCAGAAACCATCAGTGCTGCTCTTGAAGCTGCTTTAACAGGACACCCGGTCTACA
CAACCCTGCATACTTCTGGTGTTGCAGAAACGATGCGACGTCTGGTCACGTCTTTTAGCGGGGAAGAGCG
TTTGGGAAGAACCATCGATATTCTTGAAACAATTAGGCTTTGCATTTGGCAAAAACTGGTCCCAACCGTT
GATGAAAGACGTGTAGCCCTAAGGGAGTATCTGGTATTCGATGAAGAAGTGAGAGATATTCTATTGGAGG
GAGACCCTAACGAAGTGACTTCAGCCACTCGTAAGTTAGTGAGGCAAAAAGGGCAGTTAATGACTTGGGA
CGCAAAAATGAAATTTGAACAGGGGATTATCAGTGAGCGAGTTTATAAATTAATCATTGCTGGGGCCAAA
GAATATCAACAATA
Protein Sequence
>gi|54295516|ref|YP_127931.1| defect in organelle trafficking protein DotB (ATPase) [Legionella pneumophila str. Lens] MSMDNINLMPDEPTRFTPVFMDRMLEHAESLNASDITIQTGEPIFAEVYGRLLKITNRRLSNTELGDLINSIYGPNATTQLLSGKDIDTHYEFRPNRGVRYRYRVNATACLVEGHDAIQITLRTIPTTPPKLSTMNLPDNIIEAIAPQEGIVFITGATGSGKSTLLASIIRELIETSDSNRKVLTYESPIEFVYDEIETISAVVSQSEIPRHLPNFADGVRNALRRKPRLIMVGECRDAETISAALEAALTGHPVYTTLHTSGVAETMRRLVTSFSGEERLGRTIDILETIRLCIWQKLVPTVDERRVALREYLVFDEEVRDILLEGDPNEVTSATRKLVRQKGQLMTWDAKMKFEQGIISERVYKLIIAGAKEYQQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: dotB mutant is attenuated in guinea pigs (Edelstein et al., 1999).
COG COG2805NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Edelstein et al., 1999: Edelstein PH, Edelstein MA, Higa F, Falkow S. Discovery of virulence genes of Legionella pneumophila by using signature tagged mutagenesis in a guinea pig pneumonia model. Proceedings of the National Academy of Sciences of the United States of America. 1999; 96(14); 8190-8195. [PubMed: 10393970].