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Found 199 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
2329 pykF from Vibrio cholerae O395 Vibrio cholerae O395 5135110 147674848 VC0395_A0037 YP_001216011.1 pyruvate kinase Virulence factor MUTATION: pykF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2330 fbp from Vibrio cholerae O395 Vibrio cholerae O395 5135123 147674062 VC0395_A2122 YP_001218038.1 fructose-1,6-bisphosphatase Virulence factor MUTATION: fbp mutant is attenuated in mice (Merrell et al., 2002). 11952899
2331 cyaA from Vibrio cholerae O395 Vibrio cholerae O395 5135225 147673490 VC0395_A2397 YP_001218297.1 adenylate cyclase Virulence factor MUTATION: cyaA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2332 fur from Vibrio cholerae O395 Vibrio cholerae O395 5135247 147674743 VC0395_A1690 YP_001217629.1 ferric uptake regulator Virulence factor MUTATION: fur mutant is attenuated in mice (Merrell et al., 2002). 11952899
2333 mukB from Vibrio cholerae O395 Vibrio cholerae O395 5135251 147674404 VC0395_A1317 YP_001217261.1 cell division protein MukB Virulence factor MUTATION: mukB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2334 ace from Vibrio cholerae O395 Vibrio cholerae O395 5135279 147675552 VC0395_A1062 YP_001217008.1 accessory cholera enterotoxin Virulence factor TOXIN: Ace increases short-circuit current in Ussing chambers and causes fluid secretion in ligated rabbit ileal loops (Trucksis et al., 1993). 8389476
2335 frdC from Vibrio cholerae O395 Vibrio cholerae O395 5135353 147674812 VC0395_A2232 YP_001218148.1 fumarate reductase subunit C Virulence factor MUTATION: frdC mutant is attenuated in mice (Merrell et al., 2002). 11952899
2336 rfbB from Vibrio cholerae O395 Vibrio cholerae O395 5135444 147673913 VC0395_A2622 YP_001218501.1 phosphomannomutase Virulence factor MUTATION: rfbB mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2337 ubiC from Vibrio cholerae O395 Vibrio cholerae O395 5135591 147674053 VC0395_A2420 YP_001218320.1 chorismate--pyruvate lyase Virulence factor MUTATION: ubiC mutant is attenuated in mice (Merrell et al., 2002). 11952899
2338 tolBfrom Vibrio cholerae O395 Vibrio cholerae O395 5135619 147674437 VC0395_A1429 YP_001217372.1 translocation protein TolB Virulence factor MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2339 acpS from Vibrio cholerae O395 Vibrio cholerae O395 5135659 147675265 VC0395_A2035 YP_001217959.1 4'-phosphopantetheinyl transferase Virulence factor MUTATION: acpS mutant is attenuated in mice (Merrell et al., 2002). 11952899
2340 ccmF from Vibrio cholerae O395 Vibrio cholerae O395 5135811 147674378 VC0395_A1640 YP_001217579.1 cytochrome c-type biogenesis protein CcmF Virulence factor MUTATIOn: ccmF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2341 tcpT from Vibrio cholerae O395 Vibrio cholerae O395 5135974 147673300 VC0395_A0360 YP_001216316.1 toxin co-regulated pilus biosynthesis protein T Virulence factor MUTATION: tcpT mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2342 toxR Vibrio cholerae O395 5136021 147674563 VC0395_A0505 YP_001216456.1 cholera toxin transcriptional activator Virulence factor MUTATION: toxR mutant is attenuated in mice (Taylor et al., 1987). 2883655
2343 ctxA from Vibrio cholerae O395 Vibrio cholerae O395 5136023 147673805 VC0395_A1060 YP_001217006.1 cholera enterotoxin, A subunit Virulence factor TOXIN: Fluid accumulated in the rabbit intestinal loop model after 16 hours of incubation with cholera toxin, which is encoded by the genes ctxA and ctxB (Peterson and Ochoa, 1989). 2549637
2344 carB from Vibrio cholerae O395 Vibrio cholerae O395 5136051 147673654 VC0395_A1967 YP_001217891.1 carbamoyl phosphate synthase large subunit Virulence factor MUTATION: carB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2345 zot from Vibrio cholerae O395 Vibrio cholerae O395 5136175 147674144 VC0395_A1061 YP_001217007.1 zona occludens toxin Virulence factor TOXIN: The zot toxin increases the permeability of the small intestinal mucosa by affecting the structure of the intercellular tight junction, or zonula occludens (Fasano et al., 1991). 2052603
2346 gshB from Vibrio cholerae O395 Vibrio cholerae O395 5136329 147673886 VC0395_A0020 YP_001215994.1 glutathione synthetase Virulence factor MUTATION: gshB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2347 nqrE from Vibrio cholerae O395 Vibrio cholerae O395 5136378 147674521 VC0395_A1880 YP_001217804.1 Na(+)-translocating NADH-quinone reductase subunit E Virulence factor MUTATION: nqrE mutant is attenuated in mice (Merrell et al., 2002). 11952899
2348 fabG from Vibrio cholerae O395 Vibrio cholerae O395 5136416 147675453 VC0395_A1607 YP_001217548.1 3-ketoacyl-(acyl-carrier-protein) reductase Virulence factor MUTATION: fabG mutant is attenuated in mice (Merrell et al., 2002). 11952899
2349 tcpN/toxT Vibrio cholerae O395 5136424 147673596 VC0395_A0363 YP_001216319.1 TCP pilus virulence regulatory protein Virulence factor MUTATION: toxT mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2350 purD from Vibrio cholerae O395 Vibrio cholerae O395 5136447 147673352 VC0395_A2652 YP_001218530.1 phosphoribosylamine--glycine ligase Virulence factor MUTATION: purD mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2351 rpoS from Vibrio cholerae O395 Vibrio cholerae O395 5136575 147674644 VC0395_A0062 YP_001216035.1 RNA polymerase sigma factor RpoS Virulence factor MUTATION: rpoS mutants had defective colonization ability of mice intestines compared to the wild type (Merrell et al., 2000). 11083783
2352 trpG from Vibrio cholerae O395 Vibrio cholerae O395 5136631 147673994 VC0395_A0795 YP_001216745.1 anthranilate synthase component II Virulence factor MUTATION: trpG mutant is attenuated in mice (Merrell et al., 2002). 11952899
2353 purF from Vibrio cholerae O395 Vibrio cholerae O395 5136658 147673131 VC0395_A0525 YP_001216476.1 amidophosphoribosyltransferase Virulence factor MUTATION: purF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2354 purL from Vibrio cholerae O395 Vibrio cholerae O395 5136680 147673351 VC0395_A0395 YP_001216350.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in mice (Merrell et al., 2002). 11952899
2355 rpoE from Vibrio cholerae O395 Vibrio cholerae O395 5136709 147675349 VC0395_A2045 YP_001217969.1 RNA polymerase sigma factor RpoE Virulence factor MUTATION: rpoE mutant is attenuated in mice (Kovacikova and Skorupski, 2002). 12228259
2356 relA Vibrio cholerae O395 5136723 147673921 VC0395_A2029 YP_001217953.1 GTP pyrophosphokinase Virulence factor MUTATION: relA mutant is attenuated in mice (Haralalka et al., 2003). 12896985
2357 lysA from Vibrio cholerae O395 Vibrio cholerae O395 5136731 147674363 VC0395_A2394 YP_001218294.1 diaminopimelate decarboxylase Virulence factor MUTATION: lysA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2358 aceF from Vibrio cholerae O395 Vibrio cholerae O395 5136758 147674758 VC0395_A1989 YP_001217913.1 dihydrolipoamide acetyltransferase Virulence factor MUTATION: aceF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2359 tcpA from Vibrio cholerae O395 Vibrio cholerae O395 5136800 147673187 VC0395_A0353 YP_001216309.1 toxin co-regulated pilin Virulence factor MUTATION: tcpA mutant has defect in colonization of infant mice (Thelin and Taylor, 1996). 8698524
2360 acfC from Vibrio cholerae O395 Vibrio cholerae O395 5136801 147673127 VC0395_A0366 YP_001216322.1 accessory colonization factor AcfC Virulence factor MUTATION: acfC mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
2361 rfbL from Vibrio cholerae O395 Vibrio cholerae O395 5136823 147673559 VC0395_A2629 YP_001218508.1 rfbL protein Virulence factor MUTATION: rfbL mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2362 nqrF from Vibrio cholerae O395 Vibrio cholerae O395 5136909 147675137 VC0395_A1879 YP_001217803.1 Na(+)-translocating NADH-quinone reductase subunit F Virulence factor MUTATION: nqrF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2363 galM from Vibrio cholerae O395 Vibrio cholerae O395 5136975 147675555 VC0395_A1196 YP_001217142.1 aldose 1-epimerase Virulence factor MUTATION: galM mutant is attenuated in mice (Merrell et al., 2002). 11952899
2364 recO from Vibrio cholerae O395 Vibrio cholerae O395 5137028 147673381 VC0395_A2037 YP_001217961.1 DNA repair protein RecO Virulence factor MUTATION: recO mutant is attenuated in mice (Merrell et al., 2002). 11952899
2365 ilvD from Vibrio cholerae O395 Vibrio cholerae O395 5137059 147675499 VC0395_A2491 YP_001218384.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in mice (Merrell et al., 2002). 11952899
2366 deoC from Vibrio cholerae O395 Vibrio cholerae O395 5137095 147674428 VC0395_A1929 YP_001217853.1 deoxyribose-phosphate aldolase Virulence factor MUTATION: deoC mutant is attenuated in mice (Merrell et al., 2002). 11952899
2367 acfB from Vibrio cholerae O395 Vibrio cholerae O395 5137124 147673778 VC0395_A0365 YP_001216321.1 accessory colonization factor AcfB Virulence factor MUTATION: acfB mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
2368 purK from Vibrio cholerae O395 Vibrio cholerae O395 5137360 147674298 VC0395_A2468 YP_001218361.1 phosphoribosylaminoimidazole carboxylase ATPase subunit Virulence factor MUTATION: purK mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2369 pta from Vibrio cholerae O395 Vibrio cholerae O395 5137512 147675254 VC0395_A0615 YP_001216565.1 phosphate acetyltransferase Virulence factor MUTATION: pta mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2370 acfA from Vibrio cholerae O395 Vibrio cholerae O395 5137546 147674631 VC0395_A0368 YP_001216324.1 accessory colonization factor AcfA Virulence factor MUTATION: acfA mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
2371 galK from Vibrio cholerae O395 Vibrio cholerae O395 5137652 147673567 VC0395_A1197 YP_001217143.1 galactokinase Virulence factor MUTATION: galK mutant is attenuated in mice (Merrell et al., 2002). 11952899
2372 carA from Vibrio cholerae O395 Vibrio cholerae O395 5137723 147675544 VC0395_A1968 YP_001217892.1 carbamoyl phosphate synthase small subunit Virulence factor MUTATION: carA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2373 sspA from Vibrio cholerae O395 Vibrio cholerae O395 5137829 147675668 VC0395_A0108 YP_001216073.1 stringent starvation protein A Virulence factor MUTATION: sspA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2374 bioB from Vibrio cholerae O395 Vibrio cholerae O395 5137832 147673516 VC0395_A0630 YP_001216580.1 biotin synthase Virulence factor MUTATION: bioB mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2375 irgA Vibrio cholerae O395 5137888 147674899 VC0395_A0028 YP_001216002.1 enterobactin receptor Virulence factor MUTATION: irgA mutant is attenuated in mice (Goldberg et al., 1990). 2152889
2376 tcpE from Vibrio cholerae O395 Vibrio cholerae O395 5137918 147675450 VC0395_A0361 YP_001216317.1 toxin co-regulated pilus biosynthesis protein E Virulence factor MUTATION: tcpE mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
2377 zwf from Vibrio cholerae O395 Vibrio cholerae O395 5133978 147671692 VC0395_0341 YP_001215182.1 glucose-6-phosphate 1-dehydrogenase Virulence factor MUTATION: zwf mutant is attenuated in mice (Merrell et al., 2002). 11952899
2378 ydbK from Vibrio cholerae O395 Vibrio cholerae O395 5133989 147672240 VC0395_0463 YP_001215304.1 pyruvate-flavoredoxin oxidoreductase Virulence factor MUTATION: ydbK mutant is attenuated in mice (Merrell et al., 2002). 11952899
2379 ace from Vibrio cholerae O395 Vibrio cholerae O395 5134229 147672404 VC0395_0510 YP_001215349.1 accessory cholera enterotoxin Virulence factor TOXIN: Ace increases short-circuit current in Ussing chambers and causes fluid secretion in ligated rabbit ileal loops (Trucksis et al., 1993). 8389476
2380 zot from Vibrio cholerae O395 Vibrio cholerae O395 5134487 147672022 VC0395_0511 YP_001215350.1 zona occludens toxin Virulence factor TOXIN: The zot toxin increases the permeability of the small intestinal mucosa by affecting the structure of the intercellular tight junction, or zonula occludens (Fasano et al., 1991). 2052603
2381 phaC from Vibrio cholerae O395 Vibrio cholerae O395 5134754 147671535 VC0395_0628 YP_001215467.1 polyhydroxyalkanoic acid synthase Virulence factor MUTATION: phaC mutant is attenuated in mice (Merrell et al., 2002). 11952899
2382 ctxA from Vibrio cholerae O395 Vibrio cholerae O395 5134988 147672109 VC0395_0512 YP_001215351.1 cholera enterotoxin, A subunit Virulence factor TOXIN: Fluid accumulated in the rabbit intestinal loop model after 16 hours of incubation with cholera toxin, which is encoded by the genes ctxA and ctxB (Peterson and Ochoa, 1989). 2549637
2383 VCA0688 Vibrio cholerae O1 biovar El Tor str. N16961 2612154 15601445 VCA0688 AE003853 NP_233076 polyhydroxyalkanoic acid synthase Virulence factor MUTATION: VCA0688 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2384 VCA0910 Vibrio cholerae O1 biovar El Tor str. N16961 2612226 15601664 VCA0910 AE003853 NP_233295 tonB1 protein Virulence factor MUTATION: VCA0910 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2385 VCA0006 Vibrio cholerae O1 biovar El Tor str. N16961 2612229 15600777 VCA0006 AE003853 NP_232407 hypothetical protein Virulence factor MUTATION: VCA0006 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2386 VCA0903 Vibrio cholerae O1 biovar El Tor str. N16961 2612274 15601657 VCA0903 AE003853 NP_233288 hypothetical protein Virulence factor MUTATION: VCA0903 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2387 VCA0896 Vibrio cholerae O1 biovar El Tor str. N16961 2612623 15601650 VCA0896 AE003853 NP_233281 glucose-6-phosphate 1-dehydrogenase Virulence factor MUTATION: VCA0896 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2388 VCA0600 Vibrio cholerae O1 biovar El Tor str. N16961 2612672 15601358 VCA0600 AE003853 NP_232989 repressor protein PhnR, putative Virulence factor MUTATION: VCA0600 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2389 VCA0578 Vibrio cholerae O1 biovar El Tor str. N16961 2612692 15601337 VCA0578 AE003853 NP_232968 hypothetical protein Virulence factor MUTATION: VCA0578 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2390 VCA0530 Vibrio cholerae O1 biovar El Tor str. N16961 2612700 15601290 VCA0530 AE003853 NP_232921 pyruvate-flavoredoxin oxidoreductase Virulence factor MUTATION: VCA0530 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2391 VCA0583 Vibrio cholerae O1 biovar El Tor str. N16961 2612870 15601342 VCA0583 AE003853 NP_232973 hypothetical protein Virulence factor MUTATION: VCA0583 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2392 VCA0930 Vibrio cholerae O1 biovar El Tor str. N16961 2612901 15601684 VCA0930 AE003853 NP_233315 hypothetical protein Virulence factor MUTATION: VCA0930 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2393 VC0028 Vibrio cholerae O1 biovar El Tor str. N16961 2612960 15640060 VC0028 AE003852 NP_229687 dihydroxy-acid dehydratase Virulence factor MUTATION: VC0028 mutant was attenuated in mice (Merrell et al., 2002). 11952899
2394 cyaA from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2612962 15640154 VC0122 NP_229781.1 adenylate cyclase Virulence factor MUTATION: cyaA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2395 VC2426 Vibrio cholerae O1 biovar El Tor str. N16961 2612968 15642423 VC2426 HB973679 NP_232056 leader peptidase PilD Virulence factor MUTATION: VC2426 (pilD/vcpD) mutant is attenuated in mice (Marsh and Taylor, 1998). 9781884
2396 VC2433 Vibrio cholerae O1 biovar El Tor str. N16961 2612975 15642430 VC2433 AE003852 NP_232063 cyclic 3',5'-adenosine monophosphate phosphodiesterase Virulence factor MUTATION: VC2433 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2397 tolC Vibrio cholerae O1 biovar El Tor str. N16961 2612978 15642433 VC2436 NP_232066.1 outer membrane channel protein Virulence factor MUTATION: tolC mutant is deficient in intestinal colonization of mice (Bina and Mekalanos, 2001). 11402016
2398 VC2437 Vibrio cholerae O1 biovar El Tor str. N16961 2612979 0 VC2437 - - Virulence factor MUTATION: VC2437 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2399 VC2453 Vibrio cholerae O1 biovar El Tor str. N16961 2612995 15642449 VC2453 AE003852 NP_232082 hybrid sensory histidine kinase BarA Virulence factor MUTATION: barA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2400 VC2455 Vibrio cholerae O1 biovar El Tor str. N16961 2612997 15642451 VC2455 AE003852 NP_232084 hypothetical protein Virulence factor MUTATION: VC2455 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2401 acpS from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2612999 15642453 VC2457 NP_232086.1 4'-phosphopantetheinyl transferase Virulence factor MUTATION: acpS mutant is attenuated in mice (Merrell et al., 2002). 11952899
2402 recO from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613001 15642455 VC2459 NP_232088.1 DNA repair protein RecO Virulence factor MUTATION: recO mutant is attenuated in mice (Merrell et al., 2002). 11952899
2403 carB from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613058 15642386 VC2389 NP_232019.1 carbamoyl phosphate synthase large subunit Virulence factor MUTATION: carB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2404 VC2390 Vibrio cholerae O1 biovar El Tor str. N16961 2613059 15642387 VC2390 AE003852 NP_232020 carbamoyl phosphate synthase small subunit Virulence factor MUTATION: VC2390 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2405 aceF from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613082 15642410 VC2413 NP_232043.1 dihydrolipoamide acetyltransferase Virulence factor MUTATION: aceF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2406 VC2295 Vibrio cholerae O1 biovar El Tor str. N16961 2613091 15642293 VC2295 AE003852 NP_231926 Na(+)-translocating NADH-quinone reductase subunit A Virulence factor MUTATION: VC2295 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2407 VC2320 Vibrio cholerae O1 biovar El Tor str. N16961 2613116 15642318 VC2320 AE003852 NP_231951 exodeoxyribonuclease V, 135 kDa subunit Virulence factor MUTATION: VC2320 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2408 VC2290 Vibrio cholerae O1 biovar El Tor str. N16961 2613212 15642288 VC2290 AE003852 NP_231921 Na(+)-translocating NADH-quinone reductase subunit F Virulence factor MUTATION: VC2290 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2409 VC2291 Vibrio cholerae O1 biovar El Tor str. N16961 2613213 15642289 VC2291 AE003852 NP_231922 Na(+)-translocating NADH-quinone reductase subunit E Virulence factor MUTATION: VC2291 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2410 VC2206 Vibrio cholerae O1 biovar El Tor str. N16961 2613246 15642205 VC2206 AE003852 NP_231837 hypothetical protein Virulence factor MUTATION: VC2206 (flgP) mutant is defective in intestinal colonization of mice (Morris et al., 2008). 17981980
2411 fur from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613362 15642106 VC2106 NP_231738.1 ferric uptake regulator Virulence factor MUTATION: fur mutant is attenuated in mice (Merrell et al., 2002). 11952899
2412 fabG from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613400 15642023 VC2021 NP_231655.1 3-ketoacyl-(acyl-carrier-protein) reductase Virulence factor MUTATION: fabG mutant is attenuated in mice (Merrell et al., 2002). 11952899
2413 VC2030 Vibrio cholerae O1 biovar El Tor str. N16961 2613409 15642032 VC2030 AE003852 NP_231664 ribonuclease E Virulence factor MUTATION: VC2030 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2414 VC2042 Vibrio cholerae O1 biovar El Tor str. N16961 2613423 15642044 VC2042 AE003852 NP_231676 histone deacetylase/AcuC/AphA family protein Virulence factor MUTATION: aphA mutant is attenuated in mice (Kovacikova and Skorupski, 2001). 11489126
2415 VC2052 Vibrio cholerae O1 biovar El Tor str. N16961 2613432 15642052 VC2052 AE003852 NP_231684 cytochrome c-type biogenesis protein CcmF Virulence factor MUTATION: VC2052 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2416 VC2067 Vibrio cholerae O1 biovar El Tor str. N16961 2613447 15642067 VC2067 AE003852 NP_231699 MinD-related protein Virulence factor MUTATION: VC2067 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2417 tolB from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613590 15641838 VC1836 NP_231470.1 translocation protein TolB Virulence factor MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2418 VC1887 Vibrio cholerae O1 biovar El Tor str. N16961 2613641 15641889 VC1887 AE003852 NP_231521 hypothetical protein Virulence factor MUTATION: VC1887 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2419 VC1771 Vibrio cholerae O1 biovar El Tor str. N16961 2613651 15641774 VC1771 AE003852 NP_231406 hypothetical protein Virulence factor MUTATION: VC1771 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2420 mukB from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613719 15641718 VC1714 NP_231350.1 cell division protein MukB Virulence factor MUTATION: mukB mutant is attenuated in mice (Merrell et al., 2002). 11952899
2421 VC1715 Vibrio cholerae O1 biovar El Tor str. N16961 2613720 15641719 VC1715 AE003852 NP_231351 condesin subunit E Virulence factor MUTATION: VC1715 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2422 VC1716 Vibrio cholerae O1 biovar El Tor str. N16961 2613721 15641720 VC1716 AE003852 NP_231352 condesin subunit F Virulence factor MUTATION: VC1716 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2423 VC1639 Vibrio cholerae O1 biovar El Tor str. N16961 2613770 15641644 VC1639 AE003852 NP_231276 sensor histidine kinase Virulence factor MUTATION: VC1639 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2424 VC1675 Vibrio cholerae O1 biovar El Tor str. N16961 2613806 15641679 VC1675 AE003852 NP_231311 multidrug resistance protein, putative Virulence factor MUTATION: VC1675 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2425 galM from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2613848 15641602 VC1594 NP_231234.1 aldose 1-epimerase Virulence factor MUTATION: galM mutant is attenuated in mice (Merrell et al., 2002). 11952899
2426 VC1595 Vibrio cholerae O1 biovar El Tor str. N16961 2613849 15641603 VC1595 AE003852 NP_231235 galactokinase Virulence factor MUTATION: VC1595 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2427 VC0257 Vibrio cholerae O1 biovar El Tor str. N16961 2614180 15640286 VC0257 AE003853 NP_229913 transposase OrfAB, subunit B Virulence factor MUTATION: VC0257 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2428 VC0965 Vibrio cholerae O1 biovar El Tor str. N16961 2614218 15640981 VC0965 AE003852 NP_230612 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: VC0965 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2429 VC1004 Vibrio cholerae O1 biovar El Tor str. N16961 2614257 15641019 VC1004 AE003852 NP_230650 amidophosphoribosyltransferase Virulence factor MUTATION: VC1004 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2430 VC1012 Vibrio cholerae O1 biovar El Tor str. N16961 2614265 15641027 VC1012 AE003852 NP_230658 electron transport complex RsxE subunit Virulence factor MUTATION: VC1012 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2431 VC0251 Vibrio cholerae O1 biovar El Tor str. N16961 2614274 15640281 VC0251 AE003852 NP_229908 acyl protein synthase/acyl-CoA reductase RfbN Virulence factor MUTATION: VC0251 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2432 VC0249 Vibrio cholerae O1 biovar El Tor str. N16961 2614277 15640279 VC0249 AE003852 NP_229906 rfbL protein Virulence factor MUTATION: rfbL mutant is attenuated in mice (Merrell et al., 2002). 11952899
2433 VC0250 Vibrio cholerae O1 biovar El Tor str. N16961 2614278 15640280 VC0250 AE003852 NP_229907 iron-containing alcohol dehydrogenase family protein RfbM Virulence factor MUTATION: VC0250 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2434 VC1021 Vibrio cholerae O1 biovar El Tor str. N16961 2614291 15641034 VC1021 AE003852 NP_230666 LuxO repressor protein Virulence factor MUTATION: luxO mutant is defective in colonization of infant mouse intestine (Zhu et al., 2002). 11854465
2435 VC1075 Vibrio cholerae O1 biovar El Tor str. N16961 2614345 15641088 VC1075 AE003852 NP_230720 hypothetical protein Virulence factor MUTATION: VC1075 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2436 VC1098 Vibrio cholerae O1 biovar El Tor str. N16961 2614368 15641111 VC1098 AE003852 NP_230743 acetate kinase Virulence factor MUTATION: VC1098 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2437 VC0051 Vibrio cholerae O1 biovar El Tor str. N16961 2614419 15640083 VC0051 AE003852 NP_229710 phosphoribosylaminoimidazole carboxylase ATPase subunit Virulence factor MUTATION: VC0051 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2438 VC0032 Vibrio cholerae O1 biovar El Tor str. N16961 2614466 15640064 VC0032 AE003852 NP_229691 ComM-related protein Virulence factor MUTATION: VC0032 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2439 VC0036 Vibrio cholerae O1 biovar El Tor str. N16961 2614481 15640068 VC0036 AE003852 NP_229695 FixG-related protein Virulence factor MUTATION: VC0036 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2440 VC0826 Vibrio cholerae O1 biovar El Tor str. N16961 2614493 15640843 VC0826 AE003852 NP_230474 toxin co-regulated pilus biosynthesis protein P Virulence factor MUTATION: tcpP mutant is attenuated in mice (Merrell et al., 2002). 11952899
2441 VC0828 Vibrio cholerae O1 biovar El Tor str. N16961 2614495 15640845 VC0828 AE003852 NP_230476 toxin co-regulated pilin Virulence factor MUTATION: VC0828 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2442 VC0831 Vibrio cholerae O1 biovar El Tor str. N16961 2614498 15640848 VC0831 AE003852 NP_230479 toxin co-regulated pilus biosynthesis outer membrane protein C Virulence factor MUTATION: VC0831 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2443 VC0835 Vibrio cholerae O1 biovar El Tor str. N16961 2614502 15640852 VC0835 AE003852 NP_230483 toxin co-regulated pilus biosynthesis protein T Virulence factor MUTATION: VC0835 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2444 VC0836 Vibrio cholerae O1 biovar El Tor str. N16961 2614503 15640853 VC0836 AE003852 NP_230484 toxin co-regulated pilus biosynthesis protein E Virulence factor MUTATION: tcpE mutant is attenuated in mice (Merrell et al., 2002). 11952899
2445 VC0837 Vibrio 2614504 15640854 VC0837 NP_230485.1 toxin co-regulated pilus biosynthesis protein F Virulence factor MUTATION: tcpF mutant is attenuated in mice (Merrell et al., 2002). 11952899
2446 VC0869 Vibrio cholerae O1 biovar El Tor str. N16961 2614536 15640885 VC0869 AE003852 NP_230516 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: VC0869 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2447 VC0247 Vibrio cholerae O1 biovar El Tor str. N16961 2614565 15640277 VC0247 AE003852 NP_229904 lipopolysaccharide/O-antigen transport protein Virulence factor MUTATION: VC0247 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2448 VC0244 Vibrio cholerae O1 biovar El Tor str. N16961 2614566 15640274 VC0244 AE003852 NP_229901 perosamine synthase Virulence factor MUTATION: VC0244 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2449 VC1162 Vibrio cholerae O1 biovar El Tor str. N16961 2614595 15641175 VC1162 AE003852 NP_230807 hypothetical protein Virulence factor MUTATION: VC1162 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2450 VC1173 Vibrio cholerae O1 biovar El Tor str. N16961 2614606 15641186 VC1173 AE003852 NP_230818 anthranilate synthase component II Virulence factor MUTATION: VC1173 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2451 VC0192 Vibrio cholerae O1 biovar El Tor str. N16961 2614701 15640222 VC0192 AE003852 NP_229849 AraC/XylS family transcriptional regulator Virulence factor MUTATION: VC0192 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2452 VC0212 Vibrio cholerae O1 biovar El Tor str. N16961 2614702 15640242 VC0212 HB970497 NP_229869 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase Virulence factor MUTATION: VC0212 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2453 VC0242 Vibrio cholerae O1 biovar El Tor str. N16961 2614705 15640272 VC0242 AE003852 NP_229899 phosphomannomutase Virulence factor MUTATION: VC0242 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2454 VC0243 Vibrio cholerae O1 biovar El Tor str. N16961 2614706 15640273 VC0243 AE003852 NP_229900 GDP-mannose 4,6-dehydratase Virulence factor MUTATION: VC0243 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2455 VC0239 Vibrio cholerae O1 biovar El Tor str. N16961 2614707 15640269 VC0239 AE003852 NP_229896 hypothetical protein Virulence factor MUTATION: VC0239 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2456 VC1380 Vibrio cholerae O1 biovar El Tor str. N16961 2614834 15641392 VC1380 AE003852 NP_231024 hypothetical protein Virulence factor MUTATION: VC1380 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2457 VC0238 Vibrio cholerae O1 biovar El Tor str. N16961 2614849 15640268 VC0238 AE003852 NP_229895 hexapaptide repeat-containing transferase Virulence factor MUTATION: VC0238 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2458 VC0260 Vibrio cholerae O1 biovar El Tor str. N16961 2614878 15640289 VC0260 AE003852 NP_229916 mannosyl-transferase Virulence factor MUTATION: VC0260 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2459 hfq Vibrio cholerae O1 biovar El Tor str. N16961 2615060 15640374 VC0347 NP_230001.1 RNA-binding protein Hfq Virulence factor MUTATION: hfq mutant fails to colonize the suckling mouse intestine (Ding et al., 2004). 15225327
2460 VC0459 Vibrio cholerae O1 biovar El Tor str. N16961 2615121 15640486 VC0459 AE003852 NP_230113 hypothetical protein Virulence factor MUTATION: VC0459 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2461 VC0468 Vibrio cholerae O1 biovar El Tor str. N16961 2615130 15640495 VC0468 AE003852 NP_230122 glutathione synthetase Virulence factor MUTATION: VC0468 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2462 VC2506 Vibrio cholerae O1 biovar El Tor str. N16961 2615170 15642502 VC2506 AE003852 NP_232135 ATP-dependent helicase HepA Virulence factor MUTATION: VC2506 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2463 sspA from Vibrio cholerae O1 biovar El Tor str. N16961 Vibrio cholerae O1 biovar El Tor str. N16961 2615253 15640598 VC0576 NP_230227.1 stringent starvation protein A Virulence factor MUTATION: sspA mutant is attenuated in mice (Merrell et al., 2002). 11952899
2464 VC0259 Vibrio cholerae O1 biovar El Tor str. N16961 2615261 15640288 VC0259 AE003852 NP_229915 lipopolysaccharide biosynthesis protein RfbV Virulence factor MUTATION: VC0259 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2465 VC0485 Vibrio cholerae O1 biovar El Tor str. N16961 2615279 15640512 VC0485 AE003852 NP_230139 pyruvate kinase Virulence factor MUTATION: VC0485 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2466 VC0125 Vibrio cholerae O1 biovar El Tor str. N16961 2615366 15640156 VC0125 AE003852 NP_229783 diaminopimelate decarboxylase Virulence factor MUTATION: VC0125 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2467 VC0596 Vibrio cholerae O1 biovar El Tor str. N16961 2615384 15640617 VC0596 AE003852 NP_230246 dnaK suppressor protein Virulence factor MUTATION: VC0596 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2468 glmM Vibrio cholerae O1 biovar El Tor str. N16961 2615427 15640659 VC0639 AE003852 NP_230288 phosphoglucosamine mutase Virulence factor MUTATION: VC0639 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2469 VC0647 Vibrio cholerae O1 biovar El Tor str. N16961 2615437 15640667 VC0647 AE003852 NP_230296 polynucleotide phosphorylase/polyadenylase Virulence factor MUTATION: VC0647 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2470 VC2544 Vibrio cholerae O1 biovar El Tor str. N16961 2615561 15642539 VC2544 AE003852 NP_232172 fructose-1,6-bisphosphatase Virulence factor MUTATION: VC2544 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2471 VC2647 Vibrio cholerae O1 biovar El Tor str. N16961 2615664 15642642 VC2647 AE003852 NP_232275 hypothetical protein Virulence factor MUTATION: VC2347 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2472 VC2658 Vibrio cholerae O1 biovar El Tor str. N16961 2615675 15642653 VC2658 AE003852 NP_232286 fumarate reductase subunit C Virulence factor MUTATION: VC2658 mutant is attenuated in mice
2473 VC2660 Vibrio cholerae O1 biovar El Tor str. N16961 2615677 15642655 VC2660 AE003852 NP_232288 elongation factor P Virulence factor MUTATION: VC2660 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2474 VC0724 Vibrio cholerae O1 biovar El Tor str. N16961 2615733 15640743 VC0724 AE003852 NP_230373 phosphate ABC transporter, permease protein Virulence factor MUTATION: VC0724 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2475 VC0727 Vibrio cholerae O1 biovar El Tor str. N16961 2615736 15640746 VC0727 AE003852 NP_230376 transcriptional regulator PhoU Virulence factor MUTATION: phoU mutant is attenuated in mice (Merrell et al., 2002). 11952899
2476 VC0523 Vibrio cholerae O1 biovar El Tor str. N16961 2615814 15640545 VC0523 AE003852 NP_230174 putative glycerol-3-phosphate acyltransferase PlsY Virulence factor MUTATION: VC0523 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2477 VC0095 Vibrio cholerae O1 biovar El Tor str. N16961 2615822 15640127 VC0095 AE003852 NP_229754 chorismate--pyruvate lyase Virulence factor MUTATION: VC0095 mutant is attenuated in mice (Merrell et al., 2002). 11952899
2478 VC0132 Vibrio cholerae O1 biovar El Tor str. N16961 2615825 15640163 VC0132 AE003852 NP_229790 hypothetical protein Virulence factor MUTATION: VC0132 mutant is attenuated in mice (Merrell et al., 2002). 11952899
3841 ilvD from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771326 227080265 VCM66_0028 YP_002808816.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in mice (Merrell et al., 2002). 11952899
3842 purK from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771349 227080288 VCM66_0051 YP_002808839.1 phosphoribosylaminoimidazole carboxylase, ATPase subunit Virulence factor MUTATION: purK mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3843 ubiC from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771392 227080331 VCM66_0095 YP_002808882.1 chorismate-pyruvate lyase Virulence factor MUTATION: ubiC mutant is attenuated in mice (Merrell et al., 2002). 11952899
3844 cyaA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771419 227080358 VCM66_0122 YP_002808909.1 adenylate cyclase Virulence factor MUTATION: cyaA mutant is attenuated in mice (Merrell et al., 2002). 11952899
3845 lysA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771422 227080361 VCM66_0125 YP_002808912.1 diaminopimelate decarboxylase Virulence factor MUTATION: lysA mutant is attenuated in mice (Merrell et al., 2002). 11952899
3846 rfbB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771522 227080461 VCM66_0230 YP_002809012.1 phosphomannomutase Virulence factor MUTATION: rfbB mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3847 rfbL from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771529 227080468 VCM66_0237 YP_002809019.1 rfbL protein Virulence factor MUTATION: rfbL mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3848 purD from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771550 227080489 VCM66_0260 YP_002809040.1 phosphoribosylamine-glycine ligase Virulence factor MUTATION: purD mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3849 gshB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771739 227080678 VCM66_0453 YP_002809229.1 glutathione synthetase Virulence factor MUTATION: gshB mutant is attenuated in mice (Merrell et al., 2002). 11952899
3850 pykF from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771756 227080695 VCM66_0470 YP_002809246.1 pyruvate kinase I Virulence factor MUTATION: pykF mutant is attenuated in mice (Merrell et al., 2002). 11952899
3851 rpoS from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771778 227080717 VCM66_0492 YP_002809268.1 RNA polymerase sigma factor RpoS Virulence factor MUTATION: rpoS mutants are defective in colonization of mouse intestines compared to the wild type (Merrell et al., 2000). 11083783
3852 sspA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7771820 227080759 VCM66_0534 YP_002809310.1 stringent starvation protein A Virulence factor MUTATION: sspA mutant is attenuated in mice (Merrell et al., 2002). 11952899
3853 tcpA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772066 227081005 VCM66_0785 YP_002809556.1 toxin co-regulated pilin Virulence factor MUTATION: tcpA mutant is defective at colonizing infant mice (Thelin and Taylor, 1996). 8698524
3854 tcpT from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772073 227081012 VCM66_0792 YP_002809563.1 toxin co-regulated pilus biosynthesis protein T Virulence factor MUTATION: tcpT mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3855 tcpE from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772074 227081013 VCM66_0793 YP_002809564.1 toxin co-regulated pilus biosynthesis protein E Virulence factor MUTATION: tcpE mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3856 acfB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772078 227081017 VCM66_0797 YP_002809568.1 accessory colonization factor AcfB Virulence factor MUTATION: acfB mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
3857 acfC from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772079 227081018 VCM66_0798 YP_002809569.1 accessory colonization factor AcfC Virulence factor MUTATION: acfC mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
3858 acfA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772082 227081021 VCM66_0801 YP_002809572.1 accessory colonization factor AcfA Virulence factor MUTATION: acfA mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988). 2902009
3859 purL from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772106 227081045 VCM66_0826 YP_002809596.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in mice (Merrell et al., 2002). 11952899
3860 glyA-1 Vibrio cholerae M66-2 7772176 227081115 VCM66_0897 YP_002809666.1 serine hydroxymethyltransferase Virulence factor MUTATION: glyA-1 mutant is attenuated in mice (Merrell et al., 2002). 11952899
3861 purF from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772239 227081178 VCM66_0960 YP_002809729.1 amidophosphoribosyltransferase Virulence factor MUTATION: purF mutant is attenuated in mice (Merrell et al., 2002). 11952899
3862 pta from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772331 227081270 VCM66_1053 YP_002809821.1 phosphate acetyltransferase Virulence factor MUTATION: pta mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3863 bioB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772346 227081285 VCM66_1068 YP_002809836.1 biotin synthase Virulence factor MUTATION: bioB mutant is attenuated in mice (Chiang and Mekalanos, 1998). 9515705
3864 trpG from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772406 227081345 VCM66_1128 YP_002809896.1 anthranilate synthase component II Virulence factor MUTATION: trpG mutant is attenuated in mice (Merrell et al., 2002). 11952899
3865 rtxA Vibrio cholerae M66-2 7772684 227081623 VCM66_1407 YP_002810174.1 RTX toxin RtxA Virulence factor TOXIN: RTX toxin encoded by the rtxA gene, causes depolymerization of actin stress fibers and covalent cross-linking of cellular actin into dimers, trimers and higher multimers (Fullner and Mekalanos, 2000). 11032799
3866 galM from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772808 227081747 VCM66_1534 YP_002810298.1 aldose 1-epimerase Virulence factor MUTATION: galM mutant is attenuated in mice (Merrell et al., 2002). 11952899
3867 galK from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772809 227081748 VCM66_1535 YP_002810299.1 galactokinase Virulence factor MUTATION: galK mutant is attenuated in mice (Merrell et al., 2002). 11952899
3868 mukB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7772924 227081863 VCM66_1654 YP_002810414.1 cell division protein MukB Virulence factor MUTATION: mukB mutant is attenuated in mice (Merrell et al., 2002). 11952899
3869 tolB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773026 227081965 VCM66_1759 YP_002810516.1 tolB protein Virulence factor MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002). 11952899
3870 fabG from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773209 227082148 VCM66_1945 YP_002810699.1 3-oxoacyl-(acyl-carrier-protein) reductase Virulence factor MUTATION: fabG mutant is attenuated in mice (Merrell et al., 2002). 11952899
3871 ccmF from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773240 227082179 VCM66_1976 YP_002810730.1 cytochrome c-type biogenesis protein CcmF Virulence factor MUTATION: ccmF mutant is attenuated in mice (Merrell et al., 2002).
11952899
3872 sucA Vibrio cholerae M66-2 7773274 227082213 VCM66_2011 YP_002810764.1 2-oxoglutarate dehydrogenase, E1 component Virulence factor MUTATION: sucA mutant is attenuated in mice (Merrell et al., 2002). 11952899
3873 fur from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773292 227082231 VCM66_2029 YP_002810782.1 ferric uptake regulation protein Virulence factor MUTATION: fur mutant is attenuated in mice (Merrell et al., 2002). 11952899
3874 nqrF from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773475 227082414 VCM66_2213 YP_002810965.1 NADH:ubiquinone oxidoreductase, Na translocating, beta subunit Virulence factor MUTATION: nqrF mutant is attenuated in mice (Merrell et al., 2002). 11952899
3875 nqrE from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773476 227082415 VCM66_2214 YP_002810966.1 NADH:ubiquinone oxidoreductase, Na translocating, hydrophobic membrane protein NqrE Virulence factor MUTATION: nqrE mutant is attenuated in mice (Merrell et al., 2002). 11952899
3876 deoC from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773535 227082474 VCM66_2273 YP_002811025.1 deoxyribose-phosphate aldolase Virulence factor MUTATION: deoC mutant is attenuated in mice (Merrell et al., 2002). 11952899
3877 carB from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773573 227082512 VCM66_2312 YP_002811063.1 carbamoyl-phosphate synthase, large subunit Virulence factor MUTATION: carB mutant is attenuated in mice (Merrell et al., 2002). 11952899
3878 carA from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773574 227082513 VCM66_2313 YP_002811064.1 carbamoyl-phosphate synthase, small subunit Virulence factor MUTATION: carA mutant is attenuated in mice (Merrell et al., 2002). 11952899
3879 aceF from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773595 227082534 VCM66_2336 YP_002811085.1 pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase Virulence factor MUTATION: aceF mutant is attenuated in mice (Merrell et al., 2002). 11952899
3880 acpS from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773639 227082578 VCM66_2380 YP_002811129.1 holo-(acyl-carrier-protein) synthase Virulence factor MUTATION: acpS mutant is attenuated in mice (Merrell et al., 2002). 11952899
3881 recO from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773641 227082580 VCM66_2382 YP_002811131.1 DNA repair protein RecO Virulence factor MUTATION: recO mutant is attenuated in mice (Merrell et al., 2002). 11952899
3882 rpoE from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773649 227082588 VCM66_2390 YP_002811139.1 RNA polymerase sigma-E factor Virulence factor MUTATION: rpoE mutant is attenuated in mice (Kovacikova and Skorupski, 2002). 12228259
3883 fbp from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773723 227082662 VCM66_2465 YP_002811213.1 fructose-1,6-bisphosphatase Virulence factor MUTATION: fbp mutant is attenuated in mice (Merrell et al., 2002). 11952899
3884 frdC from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7773835 227082774 VCM66_2578 YP_002811325.1 fumarate reductase, 15 kDa hydrophobic protein Virulence factor MUTATION: frdC mutant is attenuated in mice (Merrell et al., 2002). 11952899
3885 phaC from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7780871 227812255 VCM66_A0646 YP_002812265.1 polyhydroxyalkanoic acid synthase Virulence factor MUTATION: phaC mutant is attenuated in mice (Merrell et al., 2002). 11952899
3886 zwf from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7781079 227812462 VCM66_A0856 YP_002812472.1 glucose-6-phosphate 1-dehydrogenase Virulence factor MUTATION: zwf mutant is attenuated in mice (Merrell et al., 2002). 11952899
3887 ydbK from Vibrio cholerae M66-2 Vibrio cholerae M66-2 7781770 227812099 VCM66_A0489 YP_002812109.1 pyruvate-flavoredoxin oxidoreductase Virulence factor MUTATION: ydbK mutant is attenuated in mice (Merrell et al., 2002). 11952899
4469 ctxB Vibrio cholerae O139 310833320 cholera toxin B subunit Virulence factor MUTATION: ctxB mutants have abolished toxicity (Jobling and Holmes, 1991).
1943708
4937 hemA Vibrio cholerae Bengal 12656010 glutamyl-tRNA reductase Virulence factor MUTATION: A hemA mutant is highly attenuated in mice and rabbits (Ravichandran et al., 2006). 16102875