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Found 61 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
1961 aroC from Burkholderia pseudomallei 1106a Burkholderia pseudomallei 1106a 4899749 126453136 BURPS1106A_1713 YP_001065984.1 chorismate synthase Virulence factor MUTATION: aroC mutant is highly attenuated in mice (Srilunchang et al., 2009). 19323044
1962 pabB from Burkholderia pseudomallei 1106a Burkholderia pseudomallei 1106a 4900497 126452015 BURPS1106A_3583 YP_001067814.1 para-aminobenzoate synthase, component I Virulence factor MUTATION: pabB mutant is attenuated in mice (Breitbach et al., 2008). 19121696
1963 pabB from Burkholderia pseudomallei 1106a Burkholderia pseudomallei 1106a 4902449 126454445 BURPS1106A_3308 YP_001067545.1 para-aminobenzoate synthase, component I Virulence factor MUTATION: pabB mutant is attenuated in mice (Breitbach et al., 2008). 19121696
1965 BURPS668_A2153 Burkholderia pseudomallei 668 4887799 126445249 BURPS668_A2153 CP000571 YP_001063147 BopA protein Virulence factor MUTATION: BopA mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1966 pabB from Burkholderia pseudomallei 668 Burkholderia pseudomallei 668 4882076 126438699 BURPS668_3556 YP_001060561.1 para-aminobenzoate synthase, component I Virulence factor MUTATION: pabB mutant is attenuated in mice (Breitbach et al., 2008). 19121696
1967 pabB from Burkholderia pseudomallei 668 Burkholderia pseudomallei 668 4882105 126440966 BURPS668_3275 YP_001060286.1 para-aminobenzoate synthase, component I Virulence factor MUTATION: pabB mutant is avirulent in mice (Breitbach et al., 2008). 19121696
1968 purM from Burkholderia pseudomallei 668 Burkholderia pseudomallei 668 4883825 126442046 BURPS668_3267 YP_001060278.1 phosphoribosylaminoimidazole synthetase Virulence factor MUTATION: purM mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1969 aroC from Burkholderia pseudomallei 668 Burkholderia pseudomallei 668 4884302 126441149 BURPS668_1689 YP_001058730.1 chorismate synthase Virulence factor MUTATION: aroC mutant is highly attenuated in mice (Srilunchang et al., 2009). 19323044
1970 sctU from Burkholderia pseudomallei 1710b Burkholderia pseudomallei 1710b 3693839 76819009 BURPS1710b_A0427 YP_335586.1 type III secretion system protein Virulence factor MUTATION: sctU mutant is attenuated in mice (Warawa and Woods, 2005). 15621426
1971 bopA Burkholderia pseudomallei 1710b 3694081 76817646 BURPS1710b_A0562 CP000125 YP_335721 BopA protein Virulence factor MUTATION: BopA mutant was attenuated in mice (Pilatz et al., 2006). 16714590
1972 sctU from Burkholderia pseudomallei 1710b Burkholderia pseudomallei 1710b 3694226 76819722 BURPS1710b_A0680 YP_335839.1 type III secretion system protein Virulence factor MUTATION: sctU mutant is attenuated in mice (Warawa and Woods, 2005). 15621426
1973 aroC from Burkholderia pseudomallei 1710b Burkholderia pseudomallei 1710b 3690536 76809035 BURPS1710b_1867 YP_333268.1 chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in mice (Srilunchang et al., 2009). 19323044
1974 pabB from Burkholderia pseudomallei 1710b Burkholderia pseudomallei 1710b 3690587 76809867 BURPS1710b_3318 YP_334690.1 chorismate binding enzyme Virulence factor MUTATION: pabB mutant is attenuated in mice (Breitbach et al., 2008). 19121696
1980 leuB Burkholderia pseudomallei K96243 3094947 53722725 BPSS1705 BX571966 YP_111710 3-isopropylmalate dehydrogenase Virulence factor MUTATION: leuB mutant is attenuated in mice (Cuccui et al., 2007). 17189432
1981 BPSS1509 Burkholderia pseudomallei K96243 3095047 53722531 BPSS1509 BX571966 YP_111516 hypothetical protein Virulence factor MUTATION: BPSS1509 mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1982 sctU from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3095565 53722427 BPSS1400 YP_111412.1 type III secretion system protein Virulence factor MUTATION: sctU mutant is attenuated in hamsters (Warawa and Woods, 2005). 15621426
1983 BPSS2074 Burkholderia pseudomallei K96243 3095712 53723092 BPSS2074 BX571966 YP_112077 senescence marker protein-30 (SMP-30) family protein Virulence factor MUTATION: BPSS2074 (lpfA) mutant is attenuated in hamsters (Boddey et al., 2007). 16987331
1984 bipD Burkholderia pseudomallei K96243 3096115 53722550 BPSS1529 BX571966 YP_111535 membrane antigen Virulence factor MUTATION: bipD mutant was attenuated in mice (Pilatz et al., 2006). 16714590
1985 BPSS1539 Burkholderia pseudomallei K96243 3096285 53722560 BPSS1539 BX571966 YP_111545 hypothetical protein Virulence factor MUTATION: BPSS1539 mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1986 bopE Burkholderia pseudomallei K96243 3096393 53722546 BPSS1525 BX571966 YP_111531 G-nucleotide exchange factor Virulence factor MUTATION: bopE mutant is attenuated in mice (Stevens et al., 2004). 15289563
1987 bsaZ Burkholderia pseudomallei K96243 3096627 53722555 BPSS1534 BX571966 YP_111540 surface presentation of antigens protein SpaS Virulence factor MUTATION: bsaZ mutant is attenuated in mouse macrophages (Stevens et al., 2002). 12410823
1988 BPSS0067 Burkholderia pseudomallei K96243 3096819 53721107 BPSS0067 BX571966 YP_110092 phospholipase C precursor Virulence factor MUTATION: BPSS0067 mutant is attenuated in mice (Tuanyok et al., 2006). 16988221
1989 BPSS2053 Burkholderia pseudomallei K96243 3096991 53723070 BPSS2053 BX571966 YP_112055 cell surface protein Virulence factor MUTATION: BPSS2053 mutant had reduced microbial adherence to human epithelial cells (Sim et al., 2008). 18927621
1990 pmlI Burkholderia pseudomallei K96243 3097087 53721909 BPSS0885 BX571966 YP_110894 N-acylhomoserine lactone synthase Virulence factor MUTATION: pmll mutant is attenuated in mice (Valade et al., 2004). 15060030
1991 BPSL1039 Burkholderia pseudomallei K96243 3091509 53718680 BPSL1039 BX571965 YP_107666 putative ABC transporter membrane protein Virulence factor MUTATION: BPSL1039 mutant is attenuated in mice (Cuccui et al., 2007). 17189432
1992 BPSL1263 Burkholderia mallei 3091526 53718898 BPSL1263 YP_107884.1 hypothetical protein Virulence factor MUTATION: BPSL1263 (cdpA) mutant has a 3-fold reduction in invasion of human lung epithelial cells and a 6-fold reduction in cytotoxicity on human macrophage cells (Lee et al., 2010). 20194589
1993 lipB from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3091586 53718053 BPSL0413 YP_107039.1 lipoyltransferase Virulence factor MUTATION: lipB mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1994 hisF from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3091767 53720740 BPSL3133 YP_109726.1 imidazole glycerol phosphate synthase subunit HisF Virulence factor MUTATION: hisF mutant is attenuated in mice and has intracellular growth defects (Pilatz et al., 2006). 16714590
1995 wcbN Burkholderia pseudomallei K96243 3091825 53720402 BPSL2793 BX571965 YP_109388 putative D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase Virulence factor MUTATION: wcbN mutant is attenuated in mice (Cuccui et al., 2007). 17189432
1996 BPSL2825 Burkholderia pseudomallei K96243 3091847 53720434 BPSL2825 BX571965 YP_109420 hypothetical protein Virulence factor MUTATION: BPSL2825 mutant is attenuated in mice (Pilatz et al., 2006). 16714590
1997 BPSL0634 Burkholderia pseudomallei K96243 3092290 53718277 BPSL0634 BX571965 YP_107263 putative oxidoreductase Virulence factor MUTATION: BPSL0634 mutant is attenuated in mice (Cuccui et al., 2007). 17189432
1998 BPSL1528 Burkholderia mallei 3092312 53719162 BPSL1528 YP_108148.1 hypothetical protein Virulence factor MUTATION: Inactivation of gene BPSL1528 leads to impaired actin tail formation, reduced intracellular survival, and high-grade attenuation of virulence in mice (Pilatz et al., 2006). 16714590
1999 aroB Burkholderia pseudomallei K96243 3092462 53720775 BPSL3168 BX571965 YP_109761 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2000 trpG Burkholderia pseudomallei K96243 3092485 53720660 BPSL3051 BX571965 YP_109646 anthranilate synthase component II Virulence factor MUTATION: trpG mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2001 purM from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3092877 53720427 BPSL2818 YP_109413.1 phosphoribosylaminoimidazole synthetase Virulence factor MUTATION: purM mutant is avirulent in mice (Propst et al., 2010). 20404077
2002 purN from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3092878 53718549 BPSL0908 YP_107535.1 phosphoribosylglycinamide formyltransferase Virulence factor MUTATION: purN mutant is attenuated in mice (Pilatz et al., 2006). 16714590
2003 wcbB Burkholderia pseudomallei K96243 3093047 53720417 BPSL2808 BX571965 YP_109403 putative capsular polysaccharide glycosyltransferase biosynthesis protein Virulence factor MUTATION: wcbB mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2004 wcbC Burkholderia pseudomallei K96243 3093048 53720416 BPSL2807 BX571965 YP_109402 putative capsular polysaccharide biosynthesis/export protein Virulence factor MUTATION: wcbC mutation is attenuated in mice (Reckseidler et al., 2001). 11119486
2005 nth from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3093395 53718738 BPSL1103 YP_107724.1 endonuclease III Virulence factor MUTATION: nth mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2006 BPSL0872 Burkholderia pseudomallei K96243 3093782 53718511 BPSL0872 BX571965 YP_107497 MviN-like protein Virulence factor MUTATION: BPSLO872 (mviN) mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells (Ling et al., 2006). 17110975
2007 BPSL0395 Burkholderia pseudomallei K96243 3093846 53718035 BPSL0395 BX571965 YP_107021 putative cytidylyltransferase Virulence factor MUTATION: BPSL0395 mutant is attenuated in mice (Pilatz et al., 2006). 16714590
2008 wzm Burkholderia pseudomallei K96243 3093941 53720414 BPSL2805 BX571965 YP_109400 putative capsular polysaccharide export ABC transporter transmembrane protein Virulence factor MUTATION: wzm mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2009 ilvI Burkholderia pseudomallei K96243 3093947 53718832 BPSL1196 HB949671 YP_107818 acetolactate synthase 3 catalytic subunit Virulence factor MUTATION: ilvI mutant is attenuated in mice (Atkins et al., 2002). 12183585
2010 fliC Burkholderia pseudomallei K96243 3094015 53720929 BPSL3319 BX571965 YP_109915 flagellin Virulence factor MUTATION: fliC mutant is attenuated in mice (Chua et al., 2003). 12654773
2011 wcbD Burkholderia pseudomallei K96243 3094162 53720415 BPSL2806 BX571965 YP_109401 putative capsule polysaccharide export ABC transporter transmembrane protein Virulence factor MUTATION: wcbD mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2012 BPSL3147 Burkholderia pseudomallei K96243 3094200 53720754 BPSL3147 BX571965 YP_109740 putative lipoprotein Virulence factor MUTATION: BPSL3147 mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2013 serC from Burkholderia pseudomallei K96243 Burkholderia pseudomallei K96243 3094241 53720129 BPSL2519 YP_109115.1 phosphoserine aminotransferase Virulence factor MUTATION: serC mutant is attenuated in mice (Rodrigues et al., 2006). 16997946
2014 recA Burkholderia pseudomallei K96243 3094325 53718415 BPSL0776 BX571965 YP_107401 recombinase A Virulence factor MUTATION: recA mutant is attenuated in mice (Cuccui et al., 2007). 17189432
2015 BPSL1876 Burkholderia pseudomallei K96243 3094734 53719489 BPSL1876 BX571965 YP_108475 putative phospholipase Virulence factor MUTATION: BPSL1876 mutant is attenuated in mice (Tuanyok et al., 2006). 16988221
2016 BPSL1705 Burkholderia pseudomallei K96243 3094881 53719320 BPSL1705 BX571965 YP_108306 hypothetical protein Virulence factor MUTATION: boaB (BPSL1705) mutant has reduced attachment to respiratory cells, and a boaA boaB double mutant was attenuated in murine macrophages (Balder et al., 2010). 20920184
3666 GBP346_A0742 Burkholderia pseudomallei MSHR346 7887507 237811015 GBP346_A0742 CP001408 YP_002895466 putative type IV pilin protein PilA Virulence factor MUTATION: pilA mutant is attenuated in mice (Essex-Lopresti et al., 2005). 15664977
3667 mviN Burkholderia pseudomallei MSHR346 7888150 237811120 GBP346_A0847 CP001408 YP_002895571 integral membrane protein MviN Virulence factor MUTATION: mviN mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells (Ling et al., 2006). 17110975
3668 purM from Burkholderia pseudomallei MSHR346 Burkholderia pseudomallei MSHR346 7888461 237813669 GBP346_A3446 YP_002898120.1 phosphoribosylformylglycinamidine cyclo-ligase Virulence factor MUTATION: purM mutant is attenuated in mice (Pilatz et al., 2006). 16714590
3669 nth from Burkholderia pseudomallei MSHR346 Burkholderia pseudomallei MSHR346 7889124 237811473 GBP346_A1203 YP_002895924.1 endonuclease III Virulence factor MUTATION: nth mutant is attenuated in mice (Cuccui et al., 2007). 17189432
3670 ppsA Burkholderia pseudomallei MSHR346 7889272 237812786 GBP346_A2540 CP001408 YP_002897237 phosphoenolpyruvate synthase Virulence factor MUTATION: ppsA mutant is attenuated in mice (Cuccui et al., 2007). 17189432
3671 hisF from Burkholderia pseudomallei MSHR346 Burkholderia pseudomallei MSHR346 7889294 237814060 GBP346_A3845 YP_002898511.1 imidazoleglycerol phosphate synthase, cyclase subunit Virulence factor MUTATION: hisF mutant is attenuated in mice (Pilatz et al., 2006). 16714590
3672 purN from B urkholderia pseudomallei MSHR346 B urkholderia pseudomallei MSHR346 7889759 237811171 GBP346_A0898 YP_002895622.1 phosphoribosylglycinamide formyltransferase Virulence factor MUTATION: purN mutant is attenuated in mice (Pilatz et al., 2006). 16714590
3673 rpoE Burkholderia pseudomallei MSHR346 7889774 237813202 GBP346_A2967 CP001408 YP_002897653 RNA polymerase sigma factor RpoE Virulence factor MUTATION: rpoE mutant is attenuated in mice (Thongboonkerd et al., 2007). 17346071
3674 lipB from Burkholderia pseudomallei MSHR346 Burkholderia pseudomallei MSHR346 7890481 237810647 GBP346_A0371 YP_002895098.1 lipoyl(octanoyl) transferase Virulence factor MUTATION: lipB mutant is attenuated in mice (Pilatz et al., 2006). 16714590
3675 serC from Burkholderia pseudomallei MSHR346 Burkholderia pseudomallei MSHR346 7890564 237813299 GBP346_A3066 YP_002897750.1 phosphoserine transaminase Virulence factor MUTATION: serC mutant is attenuated in mice (Rodrigues et al., 2006). 16997946
4883 capsular polysaccharide Burkholderia pseudomallei Virulence factor MUTATION: a capsule mutant of B. pseudomallei was attenuated in an acute respiratory murine model (Warawa et al., 2009). 19752033