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Found 18 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
4190 ruvB Borrelia burgdorferi B31 1194858 15594368 BB0022 AE000783 NP_212156 Holliday junction DNA helicase RuvB Virulence factor MUTATION: mutant showed attenuated virulence in C3H/HeN mice (Lin et al., 2009). 19997622
4191 ruvA Borrelia burgdorferi B31 1194859 15594369 BB0023 AE000783 NP_212157 Holliday junction DNA helicase RuvA Virulence factor MUTATION: mutant showed attenuated virulence in C3H/HeN mice (Lin et al., 2009). 19997622
4192 BB0098 Borrelia burgdorferi B31 1194934 15594444 BB0098 AE000783 NP_212232 recombination and DNA strand exchange inhibitor protein Virulence factor MUTATION: mutant showed attenuated virulence in C3H/HeN mice (Lin et al., 2009). 19997622
4193 BB0153 Borrelia burgdorferi B31 1194988 15594498 BB0153 AE000783 NP_212287 superoxide dismutase (sodA) Virulence factor MUTATION: sodA mutant showed complete attenuation in C3H/HeN mice compared with control strains (Esteve-Gassent et al., 2009). 19040638
4194 BB0198 Borrelia burgdorferi B31 1195033 15594543 BB0198 AE000783 NP_212332 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (spoT) Virulence factor MUTATION: rel(Bbu) deletion mutant eliminated virulence in mice (Bugrysheva et al., 2005). 16041012
4195 BB0210 Borrelia burgdorferi B31 1195047 15594555 BB0210 AE000783 NP_212344 surface-located membrane protein 1 (lmp1) Virulence factor MUTATION: deletion severely impaired mutant's ability to persist and induce disease in murine tissues (Yang et al., 2009). 19266024
4196 BB0219 Borrelia burgdorferi B31 1195056 15594564 BB0219 AE000783 NP_212353 gufA protein Virulence factor MUTATION: bmtA mutant attenuated in mice (Ouyang et al., 2009). 19218460
4197 BB0268 Borrelia burgdorferi B31 1195105 15594613 BB0268 AE000783 NP_212402 hypothetical protein Virulence factor MUTATION: mutant not infectious in murine model (Lybecker et al., 2010). 20815822
4198 BB0323 Borrelia burgdorferi B31 1195160 15594668 BB0323 AE000783 NP_212457 hypothetical protein Virulence factor MUTATION: deletion mutant unable to infect mice or ticks (Zhang et al., 2009) 19754308
4199 BB0363 Borrelia burgdorferi 1195200 15594708 BB0363 NP_212497.1 periplasmic protein Virulence factor MUTATION: mutant not infectious in mice, showed decreased motility (Sultan et al., 2010). 20444101
4200 BB0797 Borrelia burgdorferi B31 1195655 15595142 BB0797 AE000783 NP_212931 DNA mismatch repair protein MutS Virulence factor MUTATION: mutant showed attenuated virulence in C3H/HeN mice (Lin et al., 2009). 19997622
4445 bosR Borrelia burgdorferi ZS7 7106930 218249450 BbuZS7_0667 CP001205 YP_002375148 oxidative stress regulator protein BosR Virulence factor MUTATION: BosR mutant attenuated in mice (Hyde et al., 2009). 19906179
4450 cspA from Borrelia burgdorferi ZS7 Borrelia burgdorferi ZS7 7205433 219499160 BbuZS7_A59 YP_002455377.1 complement regulator-acquiring surface protein 1 (CRASP-1) Virulence factor MUTATION: mutant showed reduced ability to adhere to human PH cells (Kenedy et al., 2009). 19451251
4451 dbpA from Borrelia burgdorferi ZS7 Borrelia burgdorferi ZS7 7205446 219499176 BbuZS7_A21 YP_002455347.1 decorin-binding protein A Virulence factor MUTATION: dbpA deletion mutant was unable to colonize heart tissue of mice (Shi et al., 2008). 18195034
4452 bbk32 Borrelia burgdorferi 156a 7279517 219873298 Bbu156a_K19 CP001260 YP_002477384 fibronectin-binding protein hypothetical protein Virulence factor MUTATION: bbk32 knockout was significantly attenuated in murine model (Seshu et al., 2006). 16468997
4453 cspA from Borrelia burgdorferi 156a Borrelia burgdorferi 156a 7265888 219807322 Bbu156a_A60 YP_002477614.1 complement regulator-acquiring surface protein 1 (CRASP-1) Virulence factor MUTATION: mutant showed reduced ability to adhere to human PH cells (Kenedy et al., 2009). 19451251
4455 cspA from Borrelia burgdorferi N40 Borrelia burgdorferi N40 8319504 256055331 BbuN40_A68 YP_003110790.1 complement regulator acquiring protein 1; putative lipoprotein Virulence factor MUTATION: mutant showed reduced ability to adhere to human PH cells (Kenedy et al., 2009). 19451251
4952 fla Borrelia burgdorferi HB19 435009 flagellin Virulence factor MUTATION: A flagella-less mutant of Borrelia burgdorferi (HB19Fla-) was attenuated in immunodeficient SCID mice (Sadziene et al., 1996). 8627071