Search: for Help
Victors Home
Introduction
Statistics
News and Updates
Victors Query
Victors BLAST
Data Submission
Data Download
OHPI SPARQL Query
Documentation
FAQs
Disclaimer
Contact Us
UMMS Logo

Victors Search

Found 106 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
498 lmo0558 Listeria monocytogenes EGD-e 984498 16802601 lmo0558 NP_464086.1 hypothetical protein Virulence factor MUTATION: pgl mutant exhibited a 15 to 30 fold defect in growth in vivo (Crimmins et al., 2009). 19398547
499 lmo2821 Listeria monocytogenes EGD-e 984504 16804858 lmo2821 NP_466343.1 similar to internalin, Unknown, putative peptidoglycan bound protein (LPXTG motif) Virulence factor MUTATION: mutant attenuated in virulence after intravenous infection of mice (Sabet et al., 2005). 16177371
500 lmo2067 Listeria monocytogenes EGD-e 984795 16804106 lmo2067 NP_465591.1 similar to conjugated bile acid hydrolase Virulence factor MUTATION: deletion of bsh decreased resistance to bile, bacterial faecal carriage in guinea pigs and liver colonization in mice (Dussurget et al., 2002). 12180927
501 gtcA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 984958 16804587 lmo2549 NP_466072.1 wall teichoic acid glycosylation protein GtcA Virulence factor MUTATION: a gtcA mutant was attenuated in mice (Autret et al., 2001) 11254558
502 cheA Listeria monocytogenes EGD-e 985032 16802734 lmo0692 AL591976 NP_464219 two-component sensor histidine kinase CheA Virulence factor MUTATION: mutant reduced invasion of Caco-2 cells compared to wild type (Dons et al., 2004). 15155625
503 cheY Listeria monocytogenes EGD-e 985049 16802733 lmo0691 AL591976 NP_464218 chemotaxis response regulator CheY Virulence factor MUTATION: mutant reduced invasion of Caco-2 cells compared to wild type (Dons et al., 2004). 15155625
504 rnhB from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 985073 16803313 lmo1273 NP_464798.1 similar to ribonuclease H rnh Virulence factor MUTATION: mutant attenuated in mice, multiplication was significantly impaired (Bigot et al., 2009). 19246760
505 lmo1269 Listeria monocytogenes EGD-e 985087 16803309 lmo1269 NP_464794.1 similar to type-I signal peptidase Virulence factor MUTATION: lmo1269 (sipX) is attenuated in mice (Bonnemain et al., 2004). 14982622
506 lmo1271 Listeria monocytogenes EGD-e 985089 16803311 lmo1271 NP_464796.1 similar to signal peptidase I Virulence factor MUTATION: lmo1271 (sipZ) mutant is attenuated in mice (Bonnemain et al., 2004). 14982622
507 tig Listeria monocytogenes EGD-e 985096 16803307 lmo1267 NP_464792.1 trigger factor Virulence factor MUTATION: mutant showed reduced capacity to persist in spleens and livers of infected mice (Bigot et al., 2006). 17021213
508 iap Listeria monocytogenes EGD-e 985140 16802625 lmo0582 AL591975 NP_464110 invasion associated secreted endopeptidase Virulence factor MUTATION: mutant is strongly attenuated in mice, deletion led to abnormal cell division and loss of motility (Pilgrim et al., 2003). 12761132
509 inlA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 985151 16802477 lmo0433 NP_463962.1 Internalin A Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
510 aroA Listeria monocytogenes EGD-e 985307 16803640 lmo1600 AL591979 NP_465125 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase Virulence factor MUTATION: attenuated in mice (Loeffler et al., 2006). 16790768
511 clpB Listeria monocytogenes EGD-e 985416 16804245 lmo2206 AL591982 NP_465730 hypothetical protein Virulence factor MUTATION: mutant displayed 100 fold decrease in virulence in bacteria, also attenuated in mice (Chastanet et al., 2004). 14762012
512 lmo1745 Listeria monocytogenes EGD-e 985561 16803785 lmo1745 NP_465270.1 similar to two-component response regulator Virulence factor MUTATION: VirR deletion severely decreased virulence in mice and invasion in cell culture (Mandin et al., 2005). 16102006
513 lmo1695 Listeria monocytogenes EGD-e 985618 16803735 lmo1695 NP_465220.1 similar to putative membrane proteins Virulence factor MUTATION: attenuated in mice (Thedieck et al., 2006). 17042784
514 aroB Listeria monocytogenes EGD-e 985753 16803966 lmo1927 AL591981 NP_465451 3-dehydroquinate synthase Virulence factor MUTATION: attenuated in mice (Loeffler et al., 2006). 16790768
515 lmo1829 Listeria monocytogenes EGD-e 985887 16803869 lmo1829 NP_465354.1 similar to fibronectin binding proteins Virulence factor MUTATION: FbpA mutant attenuated in mice (Dramsi et al., 2004). 15228540
516 lmo1821 Listeria monocytogenes EGD-e 985901 16803861 lmo1821 NP_465346.1 similar to putative phosphoprotein phosphatase Virulence factor MUTATION: mutant attenuated in mice (Archambaud et al., 2005). 15813732
517 inlC Listeria monocytogenes EGD-e 985945 16803826 lmo1786 AL591981 NP_465311 internalin C Virulence factor MUTATION: attenuated virulence in mice (Engelbrecht et al., 1996). 8878044
518 lmo1076 Listeria monocytogenes EGD-e 986264 16803116 lmo1076 NP_464601.1 similar to autolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase) Virulence factor MUTATION: aut deletion mutants show reduced invasiveness and virulence in mice and guinea pigs (Cabanes et al., 2004). 15009888
519 pycA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 986269 16803112 lmo1072 NP_464597.1 highly similar to pyruvate carboxylase Virulence factor MUTATION: pycA mutant unable to replicate in mammalian cells, attenuated in mice (Schär et al., 2010). 20097852
520 dltA Listeria monocytogenes EGD-e 986449 16803014 lmo0974 AL591977 NP_464499 D-alanine--poly(phosphoribitol) ligase subunit 1 Virulence factor MUTATION: mutant displayed impaired adherence to various cell lines in vitro, and impaired virulence in mice (Abachin et al., 2002). 11849532
521 lmo0931 Listeria monocytogenes EGD-e 986568 16802971 lmo0931 NP_464456.1 similar to lipoate protein ligase A Virulence factor MUTATION: mutant strain defective for growth, less virulent in animals by a factor of 300 (O'Riordan et al., 2003). 14564012
522 lmo0135 Listeria monocytogenes EGD-e 986748 16802183 lmo0135 NP_463668.1 similar to oligopeptide ABC transport system substrate-binding proteins Virulence factor MUTATION: deletion mutant showed reduced bacterial adherence to host cells, severely attenuated in mice (Xayarath et al., 2009). 19818015
523 clpE from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 986780 16803037 lmo0997 NP_464522.1 ATP-dependent protease Virulence factor MUTATION: mutant strain was avirulent in mice, eliminated in the liver, affected cell division (Nair et al., 1999). 9987121
524 sod Listeria monocytogenes EGD-e 986791 16803479 lmo1439 NP_464964.1 superoxide dismutase Virulence factor MUTATION: deletion mutant attenuated in mice (Archambaud et al., 2006). 16905535
525 fri Listeria monocytogenes EGD-e 986847 16802983 lmo0943 AL591977 NP_464468 non-heme iron-binding ferritin Virulence factor MUTATION: mutant was impaired in ability to survive in macrophage cells and was attenuated in mice (Olsen et al., 2005). 15758237
526 inlB from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 986892 16802478 lmo0434 NP_463963.1 Internalin B Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
527 prfA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987031 16802246 lmo0200 NP_463731.1 listeriolysin positive regulatory protein Virulence factor MUTATION: attenuated in mice (Chakraborty et al., 1992). 1729245
528 plcA Listeria monocytogenes EGD-e 987032 16802247 lmo0201 NP_463732.1 phosphatidylinositol-specific phospholipase c Virulence factor MUTATION: mutant had attenuated virulence in mice, failed to grow in host tissues (Camilli et al., 1991). 1847723
529 hly from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987033 16802248 lmo0202 NP_463733.1 listeriolysin O precursor Virulence factor MUTATION: mutant strain resulted in a 100-fold virulence defect in mice, prematurely killed host cell (Glomski et al., 2002). 11901168
530 mpl from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987034 16802249 lmo0203 NP_463734.1 Zinc metalloproteinase precursor Virulence factor MUTATION: attenuated in mice (Raveneau et al., 1992). 1311708
531 actA Listeria monocytogenes EGD-e 987035 16802250 lmo0204 AL591974 NP_463735 actin-assembly inducing protein precursor Virulence factor MUTATION: mutant impaired in cell to cell spread, attenuated in maternal organs (Bakardjiev et al., 2005). 15871123
532 plcB from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987036 16802251 lmo0205 NP_463736.1 phospholipase C Virulence factor MUTATION: deletion mutants showed reduced virulence in mice, escape from vacuole and cell-to-cell spread (Smith et al., 1995). 7591052
533 flaA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987167 16802732 lmo0690 NP_464217.1 flagellin Virulence factor MUTATION: mutant strain impaired colonization in plant tissue (Gorski et al., 2009). 19357783
534 clpC from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987203 16802278 lmo0232 NP_463763.1 endopeptidase Clp ATP-binding chain C Virulence factor MUTATION: mutant strain showed a restricted capacity to grow in bone-marrow-derived macrophages, and an attenuated virulence in mice (Rouquette et al., 1996). 8885268
535 ami Listeria monocytogenes EGD-e 987254 16804596 lmo2558 AL591983 NP_466081 autolysin, amidase Virulence factor MUTATION: mutant strains showed a significant reduction in adherence to several cell types, attenuated in mice (Milohanic et al., 2001). 11251838
536 inlG Listeria monocytogenes EGD-e 987350 16802308 lmo0262 NP_463793.1 internalin G Virulence factor MUTATION: mutant showed loss in virulence, reduced numbers of viable bacteria in both liver and spleen of mice (Raffelsbauer et al., 1998). 9862466
537 inlH Listeria monocytogenes EGD-e 987355 16802309 lmo0263 NP_463794.1 internalin H Virulence factor MUTATION: mutant showed loss in virulence, reduced numbers of viable bacteria in both liver and spleen of mice (Raffelsbauer et al., 1998). 9862466
538 inlE Listeria monocytogenes EGD-e 987358 16802310 lmo0264 NP_463795.1 internalin E Virulence factor MUTATION: mutant showed loss in virulence, reduced numbers of viable bacteria in both liver and spleen of mice (Raffelsbauer et al., 1998). 9862466
539 clpP from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987364 16804506 lmo2468 NP_465991.1 ATP-dependent Clp protease proteolytic subunit Virulence factor MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and attenuated virulence in mice (Gaillot et al., 2000). 10760131
540 lmo0292 Listeria monocytogenes EGD-e 987455 16802338 lmo0292 NP_463823.1 similar to heat-shock protein htrA serine protease Virulence factor MUTATION: attenuated in mice (Wilson et al., 2006). 16369036
541 lmo2537 Listeria monocytogenes EGD-e 987487 16804575 lmo2537 NP_466060.1 similar to UDP-N-acetylglucosamine 2-epimerase Virulence factor MUTATION: mutant avirulent in mice (Dubail et al., 2006). 16952950
542 lmo0317 Listeria monocytogenes EGD-e 987534 16802362 lmo0317 NP_463847.1 similar to phosphomethylpyrimidine kinase (ThiD) Virulence factor MUTATION: knockout inhibited growth in mMWB and reduced spread in epithelial cells (Schauer et al., 2009). 19181806
543 relA from Listeria monocytogenes EGD-e Listeria monocytogenes EGD-e 987788 16803563 lmo1523 NP_465048.1 similar to (p)ppGpp synthetase Virulence factor MUTATION: impaired growth, avirulent in a murine model (Taylor et al., 2002). 11790730
544 lmo0415 Listeria monocytogenes EGD-e 987823 16802459 lmo0415 NP_463944.1 similar to endo-1,4-beta-xylanase Virulence factor MUTATION: lmo0415 (pgdA) is attenuated in mice (Boneca et al., 2007). 17215377
1419 plcB from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2797078 46906437 LMOf2365_0216 YP_012826.1 phospholipase C Virulence factor MUTATION: deletion mutants showed reduced virulence in mice, escape from vacuole and cell-to-cell spread (Smith et al., 1995). 7591052
1420 hly from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2797098 46906434 LMOf2365_0213 YP_012823.1 listeriolysin O Virulence factor MUTATION: mutant strain resulted in a 100-fold virulence defect in mice, prematurely killed host cell (Glomski et al., 2002). 11901168
1421 degU Listeria monocytogenes str. 4b F2365 2797137 46908687 LMOf2365_2488 AE017262 YP_015076 DNA-binding response regulator DegU Virulence factor MUTATION: mutant strain showed reduction in motility, attenuated in mice (Williams et al., 2005). 16213668
1422 inlF from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2797185 46906647 LMOf2365_0429 YP_013036.1 internalin Virulence factor MUTATION: deletion mutant avirulent in mice (Engelbrecht et al., 1998). 9791184
1423 recQ Listeria monocytogenes str. 4b F2365 2797731 46908944 LMOf2365_2745 YP_015333.1 ATP-dependent DNA helicase RecQ Virulence factor MUTATION: a recQ mutant was attenuated in mice (Autret et al., 2001) 11254558
1424 LMOf2365_0094 Listeria monocytogenes str. 4b F2365 2798471 46906316 LMOf2365_0094 YP_012705.1 pentapeptide repeats domain protein Virulence factor MUTATION: attenuated in mice (Reid et al., 2003). 14638794
1425 inlA from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2798475 46906689 LMOf2365_0471 YP_013078.1 internalin A Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
1426 LMOf2365_1971 Listeria monocytogenes str. 4b F2365 2798554 46908175 LMOf2365_1971 YP_014564.1 ATP-dependent DNA helicase RecQ, putative Virulence factor MUTATION: a recQ mutant was attenuated in mice (Autret et al., 2001) 11254558
1427 gtcA from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2798680 46908721 LMOf2365_2522 YP_015110.1 cell wall teichoic acid glycosylation protein GtcA Virulence factor MUTATION: a gtca mutant showed diminished ability to invade intestinal epithelial cells, was attenuated in mice (Autret et al., 2001). 11254558
1428 agrA Listeria monocytogenes str. 4b F2365 2798696 46906282 LMOf2365_0060 AE017262 YP_012671 accessory gene regulator protein A Virulence factor MUTATION: virulence of a agrA mutant was attenuated in a mouse (Autret et al., 2003). 12874326
1429 mpl from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2799022 46906435 LMOf2365_0214 YP_012824.1 zinc metallopeptidase Virulence factor MUTATION: attenuated in mice (Raveneau et al., 1992). 1311708
1430 ctsR Listeria monocytogenes str. 4b F2365 2799165 46906462 LMOf2365_0241 AE017262 YP_012851 transcriptional regulator CtsR Virulence factor MUTATION: attenuated virulence in spleens of mice (Karatzas et al., 2003). 12940983
1431 inlB from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2799227 0 LMOf2365_0472 - pseudo Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
1432 prfA from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2799457 46906432 LMOf2365_0211 YP_012821.1 listeriolysin regulatory protein Virulence factor MUTATION: attenuated in mice (Chakraborty et al., 1992). 1729245
1433 clpP from Listeria monocytogenes str. 4b F2365 Listeria monocytogenes str. 4b F2365 2799536 46908640 LMOf2365_2441 YP_015029.1 ATP-dependent Clp protease proteolytic subunit Virulence factor MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000). 10760131
1434 prsA-2 Listeria monocytogenes str. 4b F2365 2799631 46908453 LMOf2365_2252 YP_014842.1 protein export protein Virulence factor MUTATION: mutant attenuated in mice, impaired cell to cell spread in host cells (Alonzo et al., 2009). 19451247
3600 clpP from Listeria monocytogenes HCC23 Listeria monocytogenes HCC23 7078568 217964793 LMHCC_1513 YP_002350471.1 ATP-dependent Clp protease proteolytic subunit Virulence factor MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000). 10760131
3601 LMHCC_0048 Listeria monocytogenes HCC23 7078927 217963347 LMHCC_0048 YP_002349025.1 cell wall teichoic acid glycosylation protein GtcA Virulence factor MUTATION: a gtcA mutant was attenuated in mice (Autret et al., 2001) 11254558
3602 LMHCC_0614 Listeria monocytogenes HCC23 7078992 217963906 LMHCC_0614 YP_002349584.1 ATP-dependent DNA helicase, recQ Virulence factor MUTATION: a recQ mutant was attenuated in mice (Autret et al., 2001) 11254558
3603 clpP from Listeria monocytogenes HCC23 Listeria monocytogenes HCC23 7079328 217963429 LMHCC_0131 YP_002349107.1 ATP-dependent Clp protease proteolytic subunit Virulence factor MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000). 10760131
3604 srtB from Listeria monocytogenes HCC23 Listeria monocytogenes HCC23 7079719 217963658 LMHCC_0362 YP_002349336.1 sortase, SrtB family Virulence factor MUTATION: mutant showed attenuated virulence in mice (Bierne et al., 2004). 15028680
3605 LMHCC_2768 Listeria monocytogenes HCC23 7080110 217966039 LMHCC_2768 YP_002351717.1 ATP-dependent DNA helicase RecQ Virulence factor MUTATION: a recQ mutant was attenuated in mice (Autret et al., 2001) 11254558
3606 LMHCC_2601 Listeria monocytogenes HCC23 7080876 217965872 LMHCC_2601 YP_002351550.1 pentapeptide repeats domain protein Virulence factor MUTATION: attenuated in mice (Reid et al., 2003). 14638794
3607 LMHCC_1438 Listeria monocytogenes HCC23 7081139 217964719 LMHCC_1438 YP_002350397.1 Exo-glucosaminidase LytG (Exo-beta-N-acetylglucosaminidase lytG) (Peptidoglycan hydrolase lytG) (AutolysinlytG) Virulence factor MUTATION: mutant strain severely attenuated in cell culture, impaired for adhesion to certain eukaryotic cells (Wang and Lin, 2008). 18599819
3809 inlF from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702134 226223039 Lm4b_00433 YP_002757146.1 internalin, peptidoglycan bound protein (LPXTG motif) Virulence factor MUTATION: deletion mutant avirulent in mice (Engelbrecht et al., 1998). 9791184
3810 inlA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702161 226223065 Lm4b_00461 YP_002757172.1 Internalin A Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
3811 pycA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702259 226223686 Lm4b_01088 YP_002757793.1 pyruvate carboxylase Virulence factor MUTATION: pycA mutant unable to replicate in mammalian cells, attenuated in mice (Schär et al., 2010). 20097852
3812 relA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702376 226224124 Lm4b_01533 YP_002758231.1 (p)ppGpp synthetase Virulence factor MUTATION: impaired growth, avirulent in murine model (Taylor et al., 2002). 11790730
3813 gtcA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702426 226225097 Lm4b_02518 YP_002759204.1 cell wall teichoic acid glycosylation protein GtcA Virulence factor MUTATION: a gtcA mutant was attenuated in mice (Autret et al., 2001) 11254558
3814 mpl from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702498 226222832 Lm4b_00201 YP_002756939.1 Zinc metalloproteinase precursor Virulence factor MUTATION: attenuated in mice (Raveneau et al., 1992). 1311708
3815 inlB from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7702512 226223066 Lm4b_00462 YP_002757173.1 Internalin B Virulence factor MUTATION: attenuated in mice (Lingnau et al., 1995). 7558297
3816 lsp Listeria monocytogenes serotype 4b str. CLIP 80459 7702964 226224447 Lm4b_01860 YP_002758554.1 signal peptidase II Virulence factor MUTATION: mutant strain showed a reduced efficiency of phagosomal escape in eucaryotic cells and an attenuated virulence (Réglier-Poupet et al., 2003). 12975369
3817 Lm4b_01887 Listeria monocytogenes serotype 4b str. CLIP 80459 7702988 226224474 Lm4b_01887 YP_002758581.1 Hypothetical protein containing ChW-repeats Virulence factor MUTATION: attenuated in mice (Reid et al., 2003). 14638794
3818 clpE from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7703080 226223615 Lm4b_01017 YP_002757722.1 ATP-dependent protease Virulence factor MUTATION: mutant strain was avirulent in mice, eliminated in the liver, affected cell division (Nair et al., 1999). 9987121
3819 clpC from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7703657 226222861 Lm4b_00252 YP_002756968.1 endopeptidase Clp ATP-binding chain C Virulence factor MUTATION: mutant strain showed a restricted capacity to grow in bone-marrow-derived macrophages, and an attenuated virulence in mice (Rouquette et al., 1996). 8885268
3820 Lm4b_00320 Listeria monocytogenes serotype 4b str. CLIP 80459 7703714 226222928 Lm4b_00320 YP_002757035.1 heat-shock protein htrA serine protease Virulence factor MUTATION: attenuated in mice (Wilson et al., 2006). 16369036
3821 flaA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7703775 226223321 Lm4b_00718 YP_002757428.1 flagellin protein Virulence factor MUTATION: mutant strain impaired colonization in plant tissue (Gorski et al., 2009), reduced adhesion (Tresse et al., 2009). 19357783 19295651
3822 hly from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7704059 226222831 Lm4b_00200 YP_002756938.1 listeriolysin O precursor Virulence factor MUTATION: mutant strain resulted in a 100-fold virulence defect in mice, prematurely killed host cell (Glomski et al., 2002). 11901168
3823 prfA from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7704073 226222829 Lm4b_00197 YP_002756936.1 listeriolysin positive regulatory protein Virulence factor MUTATION: attenuated in mice (Chakraborty et al., 1992). 1729245
3824 clpP from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7704098 226225016 Lm4b_02437 YP_002759123.1 ATP-dependent Clp protease proteolytic subunit Virulence factor MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000). 10760131
3825 plcB from Listeria monocytogenes serotype 4b str. CLIP 80459 Listeria monocytogenes serotype 4b str. CLIP 80459 7704359 226222834 Lm4b_00203 YP_002756941.1 phospholipase C Virulence factor MUTATION: deletion mutants showed reduced virulence in mice, escape from vacuole and cell-to-cell spread (Smith et al., 1995). 7591052
3826 srtA Listeria monocytogenes serotype 4b str. CLIP 80459 7704527 226223548 Lm4b_00948 YP_002757655.1 Sortase Virulence factor MUTATION: attenuated in mice (Sabet et al., 2005). 16177371
4186 pycA from Listeria monocytogenes 08-5578 Listeria monocytogenes 08-5578 8748143 284801404 LM5578_1155 YP_003413269.1 pyruvate carboxylase Virulence factor MUTATION: pycA mutant unable to replicate in mammalian cells, attenuated in mice (Schär et al., 2010). 20097852
4187 pycA from Listeria monocytogenes 08-5923 Listeria monocytogenes 08-5923 8757905 284994546 LM5923_1109 YP_003416314.1 pyruvate carboxylase Virulence factor MUTATION: pycA mutant unable to replicate in mammalian cells, attenuated in mice (Schär et al., 2010). 20097852
4189 pLM33_p09 Listeria monocytogenes Lm1 9350422 298740856 pLM33_p09 YP_003727993.1 pLM33 0009 Virulence factor MUTATION: pLM33_p09 (ctpA) mutant is attenuated in in vivo persistence in mice (Francis and Thomas, 1997). 9049996
4837 agrD' Listeria monocytogenes DG119D 157939819 accessory gene regulator protein D Virulence factor MUTATION: agrD mutant reduced invasion of Caco-2 intestinal epithelial cells, attenuated in mice (Riedel et al., 2009).
19154329
4838 attM Listeria monocytogenes ATCC43251 2745842 putative transcriptional attenuator leader peptide Virulence factor MUTATION: attM mutant is attenuated in mice (Autret et al., 2001).
11254558
4839 CelR Virulence factor MUTATION: celR mutant is attenuated in mice (Autret et al., 2001).
11254558
4840 Dfp Listeria monocytogenes serotype 4b str. CLIP 80459 7704069 226224428 Lm4b_01841 FM242711 YP_002758535 pantothenate metabolism flavoprotein Virulence factor MUTATION: dfp mutant is attenuated in mice (Autret et al., 2001). 11254558
4841 hpt Listeria monocytogenes P14 18129341 putative hexose-6-phosphate transporter Virulence factor MUTATION: hfp deletion mutant showed attenuated virulence in mice (Chico-Calero et al., 2002).
11756655
4842 irpA Listeria monocytogenes EGD 1403357 internalin-related protein A precursor Virulence factor MUTATION: irpA mutant is attenuated in mice (Domann et al., 1997).
8975898
4843 LpeA (orf 3387.1) Listeria monocytogenes Virulence factor MUTATION: lpeA mutant strain failed to invade epithelial Caco-2 and hepatocyte TiB73 cell lines (Réglier-Poupet et al., 2003b).
12496198
4844 ORF483 Listeria monocytogenes Virulence factor MUTATION: ORF483 mutant is attenuated in mice (Autret et al., 2001). 11254558
4845 ORF626 Listeria monocytogenes Virulence factor MUTATION: ORF626 mutant is attenuated in mice (Autret et al., 2001). 11254558
4846 pbpX Listeria monocytogenes L99 307570078 penicillin-binding protein, putative Virulence factor MUTATION: pbpX mutant is attenuated in mice (Autret et al., 2001). 11254558
4847 Ptb Listeria monocytogenes serotype 4b str. CLIP 80459 7702587 226223970 Lm4b_01378 FM242711 YP_002758077 phosphotransbutyrylase Virulence factor MUTATION: ptb mutant is attenuated in mice (Autret et al., 2001). 11254558
4849 svpA Listeria monocytogenes L99 307571771 surface virulence-associated protein A Virulence factor MUTATION: svpA mutant strain strongly attenuated in mice, had restricted bacterial growth in organs (Borezée et al., 2001).
11700342
4850 YtgP Listeria monocytogenes Virulence factor MUTATION: ytgP mutant is attenuated in mice (Autret et al., 2001). 11254558
4904 mogR Listeria monocytogenes EGD-e 985015 16802716 lmo0674 AL591976 NP_464201 hypothetical protein Virulence factor MUTATION: mogR deletion mutant has a 250-fold decrease in virulence in mice and has reduced capacity for cell-to-cell spread (Gründling et al., 2004). 15302931