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Found 105 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
4201 cca Pseudomonas aeruginosa PAO1 877618 15595781 PA0584 NP_249275.1 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase Virulence factor MUTATION: cca mutant is attenuated in rats (Potvin et al., 2003). 14641575
4202 modA Pseudomonas aeruginosa PAO1 877661 15597060 PA1863 NP_250554.1 molybdate-binding periplasmic protein ModA Virulence factor MUTATION: modA mutant is attenuated in rats (Potvin et al., 2003). 14641575
4203 metE Pseudomonas aeruginosa PAO1 877662 15597123 PA1927 NP_250617.1 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase Virulence factor MUTATION: metE mutant is attenuated in rats (Potvin et al., 2003). 14641575
4204 algR Pseudomonas aeruginosa PAO1 877674 15600454 PA5261 NP_253948.1 alginate biosynthesis regulatory protein AlgR Virulence factor MUTATION: algR mutant is attenuated in mice (Lizewski et al., 2002). 12379685
4205 PA5441 Pseudomonas aeruginosa 877847 15600634 PA5441 NP_254128.1 hypothetical protein Virulence factor MUTATION: PA5441 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4206 toxA from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 877850 15596345 PA1148 NP_249839.1 exotoxin A Virulence factor TOXIN: toxA (exotoxin A) blocks protein synthesis by ADP ribosylation of elongation factor 2, thereby triggering cell death (Morlon-Guyot et al., 2009). 19380469
4207 pilY1 from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 877859 15599750 PA4554 NP_253244.1 type 4 fimbrial biogenesis protein PilY1 Virulence factor MUTATION: pilY1 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4208 pilD from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 877861 15599724 PA4528 NP_253218.1 type 4 prepilin peptidase PilD Virulence factor MUTATION: pilD mutant is attenuated in rats (Potvin et al., 2003). 14641575
4209 PA5437 Pseudomonas aeruginosa 877878 15600630 PA5437 NP_254124.1 putative transcriptional regulator Virulence factor MUTATION: PA5437 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4210 PA0151 Pseudomonas aeruginosa PAO1 877893 15595349 PA0151 NP_248841.1 putative TonB-dependent receptor Virulence factor MUTATION: PA0151 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4211 mucC Pseudomonas aeruginosa PAO1 877954 15595962 PA0765 NP_249456.1 positive regulator for alginate biosynthesis MucC Virulence factor MUTATION: mucC mutant is attenuated in rats (Potvin et al., 2003). 14641575
4212 PA5312 Pseudomonas aeruginosa 877979 15600505 PA5312 NP_253999.1 putative aldehyde dehydrogenase Virulence factor MUTATION: PA5312 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4213 wbpX Pseudomonas aeruginosa PAO1 878014 15600642 PA5449 NP_254136.1 glycosyltransferase WbpX Virulence factor MUTATION: wbpX mutant is attenuated in rats (Potvin et al., 2003). 14641575
4214 hfq from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 878015 15600137 PA4944 NP_253631.1 RNA-binding protein Hfq Virulence factor MUTATION: When compared to PAO1 wild-type and the rpoS- mutant, the hfq- mutant decreased virulence in Galleria mellonella by a factor of 1 x 10(4) and 5 x 10(3), respectively. Likewise, when compared to wild-type, the PAO1hfq- mutant was significantly attenuated in virulence when administered intraperitoneally in mice (Sonnleitner et al., 2003). 14521880
4215 pgm Pseudomonas aeruginosa 878134 15600324 PA5131 NP_253818.1 phosphoglyceromutase Virulence factor MUTATION: pgm mutant is attenuated in rats (Potvin et al., 2003). 14641575
4216 pilI from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 878186 15595607 PA0410 NP_249101.1 twitching motility protein PilI Virulence factor MUTATION: pilI mutant is attenuated in rats (Potvin et al., 2003). 14641575
4217 purD from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 878236 15600048 PA4855 NP_253542.1 phosphoribosylamine--glycine ligase Virulence factor MUTATION: purD mutant is attenuated in rats (Potvin et al., 2003). 14641575
4218 PA5327 Pseudomonas aeruginosa 878250 15600520 PA5327 NP_254014.1 putative oxidoreductase Virulence factor MUTATION: PA5327 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4219 exoT from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 878350 15595242 PA0044 NP_248734.1 exoenzyme T Virulence factor TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis (Krall et al., 2000). 10992524
4220 PA0073 Pseudomonas aeruginosa PAO1 878396 15595271 PA0073 NP_248763.1 ABC transporter ATP-binding protein Virulence factor MUTATION: PA0073 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4221 PA0041 Pseudomonas aeruginosa PAO1 878601 15595239 PA0041 NP_248731.1 hemagglutinin Virulence factor MUTATION: PA0041 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4222 estA Pseudomonas aeruginosa PAO1 878826 15600305 PA5112 NP_253799.1 esterase EstA Virulence factor MUTATION: estA mutant is attenuated in rats (Potvin et al., 2003). 14641575
4223 rhlB Pseudomonas aeruginosa PAO1 878954 15598674 PA3478 NP_252168.1 rhamnosyltransferase chain B Virulence factor MUTATION: rhlB mutant is attenuated in rats (Potvin et al., 2003). 14641575
4224 PA1157 Pseudomonas aeruginosa PAO1 879028 15596354 PA1157 NP_249848.1 two-component response regulator Virulence factor MUTATION: PA1157 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4225 pgk Pseudomonas aeruginosa 879198 15595749 PA0552 NP_249243.1 phosphoglycerate kinase Virulence factor MUTATION: pgk mutant is attenuated in rats (Potvin et al., 2003). 14641575
4226 PA1009 Pseudomonas aeruginosa PAO1 879264 15596206 PA1009 NP_249700.1 hypothetical protein Virulence factor MUTATION: PA1009 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4227 mucA Pseudomonas aeruginosa PAO1 879357 15595960 PA0763 NP_249454.1 anti-sigma factor MucA Virulence factor MUTATION: mucA mutant is attenuated in wounded alfalfa seedling infection model (Silo-Suh et al., 2002). 12426404
4228 PA0082 Pseudomonas aeruginosa PAO1 879402 15595280 PA0082 NP_248772.1 hypothetical protein Virulence factor MUTATION: PA0082 mutant is attenuated in rats (Lehoux et al., 2002). 12023080
4229 algC Pseudomonas aeruginosa PAO1 879406 15600515 PA5322 NP_254009.1 phosphomannomutase AlgC Virulence factor MUTATION: algC mutant is attenuated in neonatal mouse model of infection (Tang et al., 1996). 8557368
4230 exoY from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 879421 15597387 PA2191 NP_250881.1 adenylate cyclase ExoY Virulence factor TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells (Cowell et al., 2005). 16039071
4231 clpV1 Pseudomonas aeruginosa PAO1 879553 15595288 PA0090 NP_248780.1 ClpV1 Virulence factor MUTATION: clpV1 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4232 mdoG Pseudomonas aeruginosa PAO1 879629 15600271 PA5078 NP_253765.1 glucan biosynthesis protein G Virulence factor MUTATION: mdoG mutant is attenuated in rats (Potvin et al., 2003). 14641575
4233 purL Pseudomonas aeruginosa PAO1 879752 15598958 PA3763 NP_252452.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Potvin et al., 2003). 14641575
4234 PA4115 Pseudomonas aeruginosa 879777 15599310 PA4115 NP_252804.1 hypothetical protein Virulence factor MUTATION: PA4115 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4235 narK2 Pseudomonas aeruginosa PAO1 879781 15599071 PA3876 NP_252565.1 nitrite extrusion protein 2 Virulence factor MUTATION: narK2 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4236 PA2972 Pseudomonas aeruginosa PAO1 879799 15598168 PA2972 NP_251662.1 Maf-like protein Virulence factor MUTATION: PA2972 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4237 exoS Pseudomonas aeruginosa PAO1 879837 15599036 PA3841 NP_252530.1 exoenzyme S Virulence factor MUTATION: exoS mutant is attenuated in a silk worm oral infection model (Okuda et al., 2010). 20805335
4238 pepA Pseudomonas aeruginosa 879865 15599026 PA3831 NP_252520.1 leucyl aminopeptidase Virulence factor MUTATION: pepA mutant is attenuated in rats (Potvin et al., 2003). 14641575
4239 PA3826 Pseudomonas aeruginosa 879871 15599021 PA3826 NP_252515.1 hypothetical protein Virulence factor MUTATION: PA3826 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4240 wzz Pseudomonas aeruginosa PAO1 879922 15598356 PA3160 NP_251850.1 O-antigen chain length regulator Virulence factor MUTATION: wzz (wzz1) mutant is attenuated in mouse pneumonia model of infection (Kintz et al., 2008). 18065548
4241 galU Pseudomonas aeruginosa PAO1 879968 15597219 PA2023 NP_250713.1 UTP-glucose-1-phosphate uridylyltransferase Virulence factor MUTATION: galU mutant is attenuated in corneal mouse model of infection (Priebe et al., 2004). 15213167
4242 PA3498 Pseudomonas aeruginosa PAO1 880024 15598694 PA3498 NP_252188.1 oxidoreductase Virulence factor MUTATION: PA3498 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4243 purH Pseudomonas aeruginosa PAO1 880046 15600047 PA4854 NP_253541.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Virulence factor MUTATION: purH mutant is attenuated in rats (Potvin et al., 2003). 14641575
4244 nqrB Pseudomonas aeruginosa PAO1 880205 15598194 PA2998 NP_251688.1 Na(+)-translocating NADH-quinone reductase subunit B Virulence factor MUTATION: ngrB mutant is attenuated in rats (Potvin et al., 2003). 14641575
4245 PA3756 Pseudomonas aeruginosa PAO1 880314 15598951 PA3756 AE004091 NP_252445 hypothetical protein Virulence factor MUTATION: PA3756 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4246 thrC Pseudomonas aeruginosa PAO1 880336 15598930 PA3735 NP_252424.1 threonine synthase Virulence factor MUTATION: thrC mutant is attenuated in rats (Potvin et al., 2003). 14641575
4247 PA3001 Pseudomonas aeruginosa PAO1 880414 15598197 PA3001 NP_251691.1 glyceraldehyde-3-phosphate dehydrogenase Virulence factor MUTATION: PA3001 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4248 phzM Pseudomonas aeruginosa 880514 15599404 PA4209 NP_252898.1 putative phenazine-specific methyltransferase Virulence factor MUTATION: phzM mutant is attenuated in mice (Lau et al., 2004). 15213173
4249 PA4564 Pseudomonas aeruginosa 880908 15599760 PA4564 NP_253254.1 hypothetical protein Virulence factor MUTATION: PA4564 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4250 algW Pseudomonas aeruginosa PAO1 880976 15599642 PA4446 NP_253136.1 AlgW protein Virulence factor MUTATION: algW mutant is attenuated in rats (Potvin et al., 2003). 14641575
4251 PA4491 Pseudomonas aeruginosa 881054 15599687 PA4491 NP_253181.1 hypothetical protein Virulence factor MUTATION: PA4491 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4252 PA4489 Pseudomonas aeruginosa 881072 15599685 PA4489 NP_253179.1 hypothetical protein Virulence factor MUTATION: PA4489 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4253 PA4488 Pseudomonas aeruginosa 881219 15599684 PA4488 NP_253178.1 hypothetical protein Virulence factor MUTATION: PA4488 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4254 aprF Pseudomonas aeruginosa PAO1 881227 15596445 PA1248 NP_249939.1 alkaline protease secretion outer membrane protein AprF Virulence factor MUTATION: aprF mutant is attenuated in rats (Potvin et al., 2003). 14641575
4255 relA Pseudomonas aeruginosa PAO1 881299 15596131 PA0934 NP_249625.1 GTP pyrophosphokinase Virulence factor MUTATION: relA mutant is attenuated in D. melanogaster (Erickson et al., 2004). 15385461
4256 PA4692 Pseudomonas aeruginosa 881475 15599886 PA4692 NP_253380.1 putative sulfite oxidase subunit YedY Virulence factor MUTATION: PA4692 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4257 fur from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 881780 15599958 PA4764 NP_253452.1 ferric uptake regulation protein Virulence factor MUTATION: fur mutant is attenuated in mouse corneal scratch model (Preston et al., 1995). 7642283
4258 lasR from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 881789 15596627 PA1430 NP_250121.1 transcriptional regulator LasR Virulence factor MUTATION: lasR mutant is attenuated in neonatal mouse model of infection (Tang et al., 1996). 8557368
4259 phzS Pseudomonas aeruginosa 881836 15599413 PA4217 NP_252907.1 hypothetical protein Virulence factor MUTATION: phzS mutant is attenuated in mice (Lau et al., 2004). 15213173
4260 htpG Pseudomonas aeruginosa PAO1 881933 15596793 PA1596 NP_250287.1 heat shock protein 90 Virulence factor MUTATION: htpG mutant is attenuated in rats (Lehoux et al., 2002). 12023080
4261 fliC from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa PAO1 882052 15596289 PA1092 NP_249783.1 flagellin type B Virulence factor MUTATION: fliC mutant is attenuated in mice (Feldman et al., 1998). 9423837
4262 algU Pseudomonas aeruginosa PAO1 882125 15595959 PA0762 NP_249453.1 RNA polymerase sigma factor AlgU Virulence factor MUTATION: algU mutant is attenuated in rats (Potvin et al., 2003). 14641575
4263 PA0158 Pseudomonas aeruginosa PAO1 882140 15595356 PA0158 NP_248848.1 resistance-nodulation-cell division family transporter Virulence factor MUTATION: PA0158 mutant is attenuated in rats (Lehoux et al., 2002). 12023080
4264 PA4887 Pseudomonas aeruginosa 882278 15600080 PA4887 NP_253574.1 major facilitator transporter Virulence factor MUTATION: PA4887 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4265 nuoD Pseudomonas aeruginosa PAO1 882346 15597835 PA2639 NP_251329.1 bifunctional NADH:ubiquinone oxidoreductase subunit C/D Virulence factor MUTATION: nuoD mutant is attenuated in rats (Potvin et al., 2003). 14641575
4266 PA3286 Pseudomonas aeruginosa PAO1 882449 15598482 PA3286 NP_251976.1 3-oxoacyl-(acyl carrier protein) synthase III Virulence factor MUTATION: PA3286 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4267 pyrF Pseudomonas aeruginosa PAO1 882585 15598072 PA2876 NP_251566.1 OMP decarboxylase; OMPDCase; OMPdecase Virulence factor MUTATION: pyrF mutant is attenuated in rats (Potvin et al., 2003). 14641575
4268 PA2895 Pseudomonas aeruginosa PAO1 882601 15598091 PA2895 NP_251585.1 hypothetical protein Virulence factor MUTATION: PA2895 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4269 PA3173 Pseudomonas aeruginosa PAO1 882633 15598369 PA3173 NP_251863.1 short chain dehydrogenase Virulence factor MUTATION: PA3173 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4270 pvdS Pseudomonas aeruginosa PAO1 882839 15597622 PA2426 NP_251116.1 extracytoplasmic-function sigma-70 factor Virulence factor MUTATION: pvdS mutant is attenuated in rabbit aortic endocarditis model (Xiong et al., 2000). 10720526
4399 mvfR Pseudomonas aeruginosa UCBPP-PA14 4379987 116048931 PA14_51340 YP_792268.1 transcriptional regulator MvfR Virulence factor MUTATION: mvfR (pho34B12) mutant is attenuated in burned mouse model (Rahme et al., 1997). 9371831
4400 exoU from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4380009 116048914 PA14_51530 YP_792285.1 ExoU Virulence factor MUTATION: exoU mutant is avirulent in Dictyostelium discoideum, a genetically tractable eukaryotic organism (Pukatzki et al., 2002). 11867744
4401 fliC from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4380057 116049021 PA14_50290 YP_792177.1 flagellin type B Virulence factor MUTATION: fliC mutant is attenuated in mice (Feldman et al., 1998). 9423837
4402 flhB from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4380176 116049394 PA14_45720 YP_791803.1 flagellar biosynthesis protein FlhB Virulence factor MUTATION: flhB mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4403 PA14_38610 Pseudomonas aeruginosa UCBPP-PA14 4380287 116049953 PA14_38610 YP_791237.1 hypothetical protein Virulence factor MUTATION: PA14_38610 mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4404 PA14_37650 Pseudomonas aeruginosa UCBPP-PA14 4380319 116050024 PA14_37650 YP_791162.1 hypothetical protein Virulence factor MUTATION: PA14_37650 mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4405 pscJ Pseudomonas aeruginosa UCBPP-PA14 4380359 116049673 PA14_42270 YP_791522.1 pscJ type III export protein Virulence factor MUTATION: pscJ mutant is attenuated in Dictyostelium discoideum, a genetically tractable eukaryotic organism (Pukatzki et al., 2002). 11867744
4406 PA14_33610 Pseudomonas aeruginosa UCBPP-PA14 4380463 116050342 PA14_33610 YP_790841.1 peptide synthase Virulence factor MUTATION: PA14_33610 (pvdI) mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4407 gacA Pseudomonas aeruginosa UCBPP-PA14 4380617 116050573 PA14_30650 YP_790608.1 response regulator GacA Virulence factor MUTATION: gacA mutant is attenuated in burned mouse model (Rahme et al., 1997). 9371831
4408 PA14_41070 Pseudomonas aeruginosa UCBPP-PA14 4381036 116049764 PA14_41070 YP_791429.1 hypothetical protein Virulence factor MUTATION: kerV (PA14_41070) mutant is attenuated in mice (An et al., 2009). 19779606
4409 prpR Pseudomonas aeruginosa UCBPP-PA14 4381387 116050154 PA14_36000 YP_791029.1 propionate catabolism operon regulator Virulence factor MUTATION: prpR mutant is attenuated in mice and Drosophila melanogaster (Kim et al., 2008). 18591226
4410 toxA from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4381678 116049080 PA14_49560 YP_792118.1 exotoxin A precursor Virulence factor MUTATION: toxA mutant is attenuated in burned mouse model (Rahme et al., 1995). 7604262
4411 exoT from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4381738 116053766 PA14_00560 YP_788201.1 exoenzyme T Virulence factor TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis (Krall et al., 2000). 10992524
4412 pilF Pseudomonas aeruginosa 4381875 116051830 PA14_14850 YP_789327.1 type 4 fimbrial biogenesis protein PilF Virulence factor MUTATION: pilF mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4413 PA14_35740 Pseudomonas aeruginosa UCBPP-PA14 4382109 116050177 PA14_35740 YP_791006.1 putative transposase Virulence factor MUTATION: tpnA mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4414 prpL Pseudomonas aeruginosa UCBPP-PA14 4382190 116052217 PA14_09900 YP_788939.1 Pvds-regulated endoprotease, lysyl class Virulence factor MUTATION: prpL mutant is attenuated in rats (Wilderman et al., 2001). 11500408
4415 pilD from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4382650 116052560 PA14_58770 YP_792875.1 type 4 prepilin peptidase PilD Virulence factor MUTATION: pilD mutant is attenuated in rats (Potvin et al., 2003). 14641575
4416 lasR from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4382864 116049375 PA14_45960 YP_791822.1 transcriptional regulator LasR Virulence factor MUTATION: lasR mutant is avirulent in Dictyostelium discoideum (Pukatzki et al., 2002). 11867744
4417 katA Pseudomonas aeruginosa UCBPP-PA14 4382943 116052272 PA14_09150 YP_788883.1 catalase Virulence factor MUTATION: katA mutant is attenuated in Drosophila melanogaster and in mice (Lee et al., 2005). 15972537
4418 PA14_03120 Pseudomonas aeruginosa UCBPP-PA14 4383664 116053966 PA14_03120 YP_788404.1 putative transcriptional regulator Virulence factor MUTATION: PA14_03120 (hudR) mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4419 PA14_03530 Pseudomonas aeruginosa UCBPP-PA14 4383677 116053999 PA14_03530 YP_788441.1 transcriptional regulator Virulence factor MUTATION: PA14_03530 mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4420 PA14_04850 Pseudomonas aeruginosa UCBPP-PA14 4383758 116054099 PA14_04850 YP_788542.1 hypothetical protein Virulence factor MUTATION: PA14_04850 mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4421 pilI from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4383800 116054141 PA14_05340 YP_788584.1 twitching motility protein PilI Virulence factor MUTATION: pilI mutant is attenuated in rats (Potvin et al., 2003). 14641575
4422 exoY from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4384258 116054461 PA14_36345 YP_791058.1 adenylate cyclase ExoY Virulence factor TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells (Cowell et al., 2005). 16039071
4423 fabF1 Pseudomonas aeruginosa UCBPP-PA14 4384346 116050967 PA14_25690 YP_790208.1 3-oxoacyl-(acyl carrier protein) synthase II Virulence factor MUTATION: fabF1 mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4424 wspF Pseudomonas aeruginosa UCBPP-PA14 4384652 116051700 PA14_16480 YP_789461.1 chemotaxis-specific methylesterase Virulence factor MUTATION: wspF mutant is attenuated in Drosophila melanogaster (Kim et al., 2008). 18591226
4425 dsbA Pseudomonas aeruginosa UCBPP-PA14 4385158 116053639 PA14_72450 YP_793966.1 thiol:disulfide interchange protein DsbA Virulence factor MUTATION: dsbA mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4426 plcH Pseudomonas aeruginosa UCBPP-PA14 4385302 116048767 PA14_53360 YP_792433.1 hemolytic phospholipase C precursor Virulence factor MUTATION: plcH mutant is attenuated in burned mouse model (Rahme et al., 1995). 7604262
4427 pilY1 from Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14 4385727 116052698 PA14_60310 YP_793014.1 type 4 fimbrial biogenesis protein PilY1 Virulence factor MUTATION: pilY1 mutant is attenuated in rats (Potvin et al., 2003). 14641575
4428 PA14_37260 Pseudomonas aeruginosa UCBPP-PA14 4385800 116050053 PA14_37260 YP_791133.1 putative porin Virulence factor MUTATION: opdO mutant is attenuated in Drosophila melanogaster and in mice (Kim et al., 2008). 18591226
4446 exoT from Pseudomonas aeruginosa LESB58 Pseudomonas aeruginosa LESB58 7175181 218888792 PLES_00451 YP_002437656.1 exoenzyme T Virulence factor TOXIN: exoT interferes with Rho signal transduction pathways, which regulate actin organization, exocytosis, cell cycle progression, and phagocytosis (Krall et al., 2000). 10992524
4447 exoY from Pseudomonas aeruginosa LESB58 Pseudomonas aeruginosa LESB58 7177486 218891856 PLES_31341 YP_002440723.1 adenylate cyclase ExoY Virulence factor TOXIN: exoY is an adenylate cyclase that causes actin disruption in epithelial cells (Cowell et al., 2005). 16039071
4448 toxA from Pseudomonas aeruginosa LESB58 Pseudomonas aeruginosa LESB58 7178280 218892886 PLES_41711 YP_002441755.1 exotoxin A precursor Virulence factor TOXIN: toxA (exotoxin A) blocks protein synthesis by ADP ribosylation of elongation factor 2, thereby triggering cell death (Morlon-Guyot et al., 2009). 19380469
4449 fliC from Pseudomonas aeruginosa LESB58 Pseudomonas aeruginosa LESB58 7178326 218892944 PLES_42291 YP_002441813.1 flagellin type B Virulence factor MUTATION: fliC mutant is attenuated in mice (Feldman et al., 1998). 9423837
4865 LPS Pseudomonas aeruginosa Virulence factor MUTATION: an LPS mutant was nonvirulent in a burned mouse model of infection (Cryz et al., 1984). 6425224