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Found 47 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
4286 oppF Staphylococcus aureus subsp. aureus N315 1122975 15925909 SA0198 NP_373442.1 oligopeptide transport ATP-binding protein Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4287 oppD Staphylococcus aureus subsp. aureus N315 1123664 15926577 SA0847 NP_374110.1 oligopeptide transport system ATP-binding protein OppD homologue Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4288 purL Staphylococcus aureus subsp. aureus N315 1123744 15926655 SA0921 NP_374188.1 phosphoribosylformylglycinamidine synthase II Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4289 SA1062 Staphylococcus aureus subsp. aureus N315 1123893 15926802 SA1062 NP_374335.1 hypothetical protein Virulence factor MUTATION: SA1062 (stp1) mutant is attenuated in mice (Burnside et al., 2010). 20552019
4290 SA1063 Staphylococcus aureus subsp. aureus N315 1123894 15926803 SA1063 NP_374336.1 protein kinase Virulence factor MUTATION: stk1 (SA1063) mutant is attenuated in mice (Débarbouillé et al., 2009). 19395491
4291 recA from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1123959 15926868 SA1128 NP_374401.1 recombinase A Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4292 thrB Staphylococcus aureus subsp. aureus N315 1124002 15926911 SA1166 NP_374444.1 homoserine kinase homolog Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4293 citB Staphylococcus aureus subsp. aureus N315 1124021 15926930 SA1184 NP_374463.1 aconitate hydratase Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4294 msrA Staphylococcus aureus subsp. aureus N315 1124032 15926941 SA1194 NP_374474.1 peptide methionine sulfoxide reductase homolog Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4295 msrR Staphylococcus aureus subsp. aureus N315 1124033 15926942 SA1195 NP_374475.1 peptide methionine sulfoxide reductase regulator MsrR Virulence factor MUTATION: mutant displayed reduced ability to colonize and reduced virulence in nematodes and rat endocarditis (Hübscher et al., 2009). 19459977
4296 trpD Staphylococcus aureus subsp. aureus N315 1124040 15926949 SA1201 NP_374482.1 anthranilate phosphoribosyltransferase Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4297 trpB Staphylococcus aureus subsp. aureus N315 1124043 15926952 SA1204 NP_374485.1 tryptophan synthase subunit beta Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4298 trpA Staphylococcus aureus subsp. aureus N315 1124044 15926953 SA1205 NP_374486.1 tryptophan synthase subunit alpha Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4299 femA from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1124045 15926954 SA1206 NP_374487.1 factor essential for expression of methicillin resistance Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4300 femB Staphylococcus aureus subsp. aureus N315 1124046 15926955 SA1207 NP_374488.1 FemB protein Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4301 opp-2C from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1124052 15926961 SA1213 NP_374494.1 oligopeptide transporter permease Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4302 asd Staphylococcus aureus subsp. aureus N315 1124065 15926974 SA1226 NP_374507.1 aspartate semialdehyde dehydrogenase Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4303 lysA Staphylococcus aureus subsp. aureus N315 1124071 15926980 SA1232 NP_374513.1 diaminopimelate decarboxylase Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4304 braB from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1124078 15926987 SA1239 NP_374520.1 branched-chain amino acid carrier protein Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4305 odhB Staphylococcus aureus subsp. aureus N315 1124083 15926992 SA1244 NP_374525.1 dihydrolipoamide succinyltransferase Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4306 SA1262 Staphylococcus aureus subsp. aureus N315 1124100 15927010 SA1262 NP_374543.1 hypothetical protein Virulence factor MUTATION: SA1262 (cvfC3) mutant is attenuated in silkworms (Ikuo et al., 2010). 20347953
4307 dinG from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1124126 15927036 SA1288 NP_374569.1 ATP-dependent DNA helicase dinG Virulence factor MUTATION: attenuated in murine model (Begun et al., 2005). 15664928
4308 SA1453 Staphylococcus aureus subsp. aureus N315 1124296 15927206 SA1453 NP_374739.1 hypothetical protein Virulence factor MUTATION: SA1453 (cymR) mutant is attenuated in mice (Soutourina et al., 2010). 20485570
4309 clpX Staphylococcus aureus subsp. aureus N315 1124343 15927253 SA1498 NP_374786.1 ATP-dependent protease ATP-binding subunit ClpX Virulence factor MUTATION: attenuated in murine model (Mei et al., 1997). 9383163
4310 fbp from Staphylococcus aureus subsp. aureus N315 Staphylococcus aureus subsp. aureus N315 1125231 15928095 SA2304 NP_375628.1 fructose-bisphosphatase Virulence factor MUTATION: attenuated in murine model (Begun et al., 2005). 15664928
4311 braB from Staphylococcus aureus subsp. aureus Mu50 Staphylococcus aureus subsp. aureus Mu50 1121382 15924397 SAV1407 NP_371931.1 branched-chain amino acid carrier protein Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4312 mprF from Staphylococcus aureus subsp. aureus MRSA252 Staphylococcus aureus subsp. aureus MRSA252 2861306 49483553 SAR1372 YP_040777.1 hypothetical protein Virulence factor MUTATION: mprF mutant is attenuated in mice (Peschel et al., 2001). 11342591
4319 opp-2C from Staphylococcus aureus subsp. aureus MW2 Staphylococcus aureus subsp. aureus MW2 1003381 21282998 MW1269 NP_646086.1 oligopeptide transporter permease Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4320 braB from Staphylococcus aureus subsp. aureus MW2 Staphylococcus aureus subsp. aureus MW2 1003409 21283026 MW1297 NP_646114.1 branched-chain amino acid carrier protein Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4321 dinG from Staphylococcus aureus subsp. aureus MW2 Staphylococcus aureus subsp. aureus MW2 1003457 21283074 MW1345 NP_646162.1 ATP-dependent DNA helicase dinG Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4386 mprF from Staphylococcus aureus RF122 Staphylococcus aureus RF122 3793454 82750952 SAB1216 YP_416693.1 hypothetical protein Virulence factor MUTATION: mprF mutant is attenuated in mice (Peschel et al., 2001). 11342591
4387 recA from Staphylococcus aureus subsp. aureus NCTC 8325 Staphylococcus aureus subsp. aureus NCTC 8325 3919993 228937974 SAOUHSC_01262 YP_499795.2 recombinase A Virulence factor MUTATION: recA mutant is attenuated in mice (Mei et al., 1997). 9383163
4388 SAOUHSC_01373 Staphylococcus aureus subsp. aureus NCTC 8325 3920782 88195100 SAOUHSC_01373 YP_499900.1 methicillin resistance factor, FemA, putative Virulence factor MUTATION: femA mutant is attenuated in mice (Mei et al., 1997). 9383163
4431 tilS Staphylococcus aureus subsp. aureus str. Newman 5330252 151220683 NWMN_0471 YP_001331505.1 hypothetical protein Virulence factor MUTATION: mutant attenuated in a C. elegans-killing model (Begun et al., 2005). 15664928
4432 fbp from Staphylococcus aureus subsp. aureus str. Newman Staphylococcus aureus subsp. aureus str. Newman 5331488 151222626 NWMN_2414 YP_001333448.1 fructose-1,6-bisphosphatase Virulence factor MUTATION: mutant attenuated in a C. elegans-killing model (Begun et al., 2005). 15664928
4433 ccpA Staphylococcus aureus subsp. aureus str. Newman 5331715 151221841 NWMN_1629 YP_001332663.1 catabolite control protein A Virulence factor MUTATION: mutant displayed reduced replication and infection in murine model (Li et al., 2010). 20525824
4434 pyrAA Staphylococcus aureus subsp. aureus str. Newman 5332320 151221325 NWMN_1113 YP_001332147.1 carbamoyl phosphate synthase small subunit Virulence factor MUTATION: mutant attenuated in a Caenorhabditis elegans-killing model (Begun et al., 2005). 15664928
4435 braB from Staphylococcus aureus subsp. aureus Mu3 Staphylococcus aureus subsp. aureus Mu3 5560751 156979726 SAHV_1395 YP_001441985.1 branched-chain amino acid carrier protein Virulence factor MUTATION: mutant attenuated in murine infection model (Begun et al., 2005). 15664928
4436 SAHV_0924 Staphylococcus aureus subsp. aureus Mu3 5560784 156979255 SAHV_0924 YP_001441514.1 hypothetical protein Virulence factor MUTATION: NagD mutant attenuated in C. Elegans-killing model (Begun et al., 2005). 15664928
4437 mgrA Staphylococcus aureus subsp. aureus Mu3 5561057 156979014 SAHV_0683 YP_001441273.1 MarR family transcriptional regulator Virulence factor MUTATION: mutant showed less bacterial persistence in kidneys and attenuated virulence in mice (Jonsson et al., 2008). 18692591
4466 isdH Staphylococcus aureus 04-02981 285817413 Cell surface receptor IsdH for hemoglobin-haptoglobin complexes Virulence factor MUTATION: Mutant showed attenuated virulence in mouse model (Visai et al., 2009).
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19246738
4467 rsh Staphylococcus aureus Virulence factor MUTATION: rsh mutant less virulent in animal model (Geiger et al., 2010).
20212088
4873 Type 8 capsular polysaccharide (CP8) Staphylococcus aureus Virulence factor MUTATION: In a mouse infection model of bacteremia, the CP8-overproducing strain persisted longer in the bloodstream, the liver, and the spleen in mice than the parent strain (Luong and Lee, 2002). 12065477
4880 Type 5 capsular polysaccharide (CP5) Staphylococcus aureus Virulence factor MUTATION: Wild type S. aureus with a CP5 capsule were more virulent in mice than CP5 mutants (Thakker et al., 1998). 9784520
4934 aroA Staphylococcus aureus subsp. aureus ED98 8614197 269203089 SAAV_1451 CP001781 YP_003282358 3-phosphoshikimate 1-carboxyvinyltransferase Virulence factor MUTATION: An aroA mutant is attenuated in mice (Buzzola et al., 2006). 16714581
5017 spa Staphylococcus aureus subsp. aureus str. Newman 5332074 151220267 NWMN_0055 AP009351 YP_001331090 immunoglobulin G binding protein A precursor (protein A) Virulence factor An isogenic spa deletion variant S. aureus Newman Δspa was generated. After intraperitoneal challenge with 2 × 108 CFU of wild-type S. aureus Newman, 60% of animals succumbed to challenge. In contrast, animals infected with the isogenic mutant resulted in only 25% mortality. In addition, the spa mutant displayed a consistent survival defect when examined in naive mouse blood. These results suggest that SpA is a crucial virulence factor for lethal infections of S. aureus in mice (Kim et al., 2010). 20713595
5018 hla Staphylococcus aureus subsp. aureus str. Newman 5330660 151221285 NWMN_1073 AP009351 YP_001332107 alpha-hemolysin precursor Virulence factor Replacement of hla with the hla:erm allele completely abolished the ability of S. aureus LAC to cause lung infections in C57BL/6J mice (Bubeck Wardenburg et al., 2007). 18064027