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Found 81 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
1 pCJ01p4 Campylobacter jejuni 4362678 115534244 pCJ01p4 AF301164 YP_783826 hypothetical protein Virulence factor MUTATION: Mutation of plasmid gene ORF3 (comB3) reduced adherence/invasion of INT407 cells to approximately 1/3 of wild type strain 81-176 (Bacon et al., 2000).
10899834
802 Cj0019c Campylobacter jejuni subsp. jejuni NCTC 11168 904357 218561712 Cj0019c AL111168 YP_002343491 putative MCP-domain signal transduction protein Virulence factor MUTATION: a Cj0019c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
803 Cj0020c Campylobacter jejuni subsp. jejuni NCTC 11168 904360 218561713 Cj0020c AL111168 YP_002343492 cytochrome C551 peroxidase Virulence factor MUTATION: a Cj0020c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
804 fliA Campylobacter jejuni subsp. jejuni NCTC 11168 904393 218561746 Cj0061c AL111168 YP_002343525 flagellar biosynthesis sigma factor Virulence factor MUTATION: fliA mutants showed reduced motility (25% that of the wild type) and did not colonize a chicken cecum (Fernando et al., 2007) 17761334
805 Cj0248 Campylobacter jejuni subsp. jejuni NCTC 11168 904574 218561911 Cj0248 AL111168 YP_002343690 hypothetical protein Virulence factor MUTATION: a Cj0248 C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
806 motB from Campylobacter jejuni subsp. jejuni NCTC 11168 Campylobacter jejuni subsp. jejuni NCTC 11168 904660 15791704 Cj0336c NP_281527.1 flagellar motor protein MotB Virulence factor MUTATION: a Cj0336c mutant C. jejuni was attenuated for colonization of the chicken caeca (Hendrixson and DiRita, 2004) 15066034
807 motA Campylobacter jejuni subsp. jejuni NCTC 11168 904661 218561996 Cj0337c AL111168 YP_002343775 flagellar motor protein MotA Virulence factor MUTATION: a Cj0337c C. jejuni mutant was attenuated for colonization of the chicken caeca (Hendrixson and DiRita, 2004) 15066034
808 Cj0415 Campylobacter jejuni subsp. jejuni NCTC 11168 904739 218562073 Cj0415 AL111168 YP_002343852 putative GMC oxidoreductase subunit Virulence factor MUTATION: a cj0415 mutant was impaired in establishing chicken colonization (Pajaniappan et al., 2008) 18284594
809 Cj0454c Campylobacter jejuni subsp. jejuni NCTC 11168 904777 218562109 Cj0454c AL111168 YP_002343888 hypothetical protein Virulence factor MUTATION: a Cj0454c C. jejuni mutant was attenuated for colonziation of the chick caeca (Hendrixson and DiRita, 2004) 15066034
810 Cj0456c Campylobacter jejuni subsp. jejuni NCTC 11168 904779 218562111 Cj0456c AL111168 YP_002343890 hypothetical protein Virulence factor MUTATION: a Cj0456c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
811 Cj0618 Campylobacter jejuni subsp. jejuni NCTC 11168 904945 218562269 Cj0618 AL111168 YP_002344048 hypothetical protein Virulence factor MUTATION: a Cj0618 C. jejuni mutant was attenuated for the colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
812 Cj0629 Campylobacter jejuni subsp. jejuni NCTC 11168 904959 15791989 Cj0629 NP_281812 lipoprotein Virulence factor MUTATION: Cj0629 (capA) mutant had a significantly reduced capacity for association with and invasion of Caco-2 cells and failed to colonize and persist in chickens (Ashgar et al., 2007). 17172331
813 rpoN Campylobacter jejuni subsp. jejuni NCTC 11168 904991 218562314 Cj0670 AL111168 YP_002344093 RNA polymerase factor sigma-54 Virulence factor MUTATION: rpoN mutant cells lacked the spiral shape of C. jejuni and motility was reduced to 10% of the wild-type, mutants also showed significant colonization defects of a chicken cecum (Fernando et al., 2007) 17761334
814 pta Campylobacter jejuni subsp. jejuni NCTC 11168 905007 218562327 Cj0688 AL111168 YP_002344106 putative phosphate acetyltransferase Virulence factor MUTATION: a Cj0688 C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
815 flaC Campylobacter jejuni subsp. jejuni NCTC 11168 905038 218562359 Cj0720c AL111168 YP_002344138 flagellin Virulence factor MUTATION: Invasion of HEp-2 cells by flaC null mutants was reduced to a level of 14% compared with wild type (Song et al., 2004) 15228533
816 Cj0903c Campylobacter jejuni subsp. jejuni NCTC 11168 905201 218562523 Cj0903c AL111168 YP_002344302 putative amino-acid transport protein Virulence factor MUTATION: a Cj0903c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
817 ciaB from Campylobacter jejuni subsp. jejuni NCTC 11168 Campylobacter jejuni subsp. jejuni NCTC 11168 905214 218562533 Cj0914c AL111168 YP_002344312 CiaB protein Virulence factor MUTATION: C. jejuni ciaB null mutants had a significant reduction in internalization (Konkel et al., 1999) 10361274
818 aas Campylobacter jejuni subsp. jejuni NCTC 11168 905232 218562557 Cj0938c AL111168 YP_002344336 2-acyl-glycerophospho-ethanolamine acyltransferase Virulence factor MUTATION: a Cj0938c (aas) C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
819 Cj0977 Campylobacter jejuni subsp. jejuni NCTC 11168 905268 218562593 Cj0977 AL111168 YP_002344372 hypothetical protein Virulence factor MUTATION: A Cj0977 mutant strain is fully motile but significantly reduced in the invasion of intestinal epithelial cells in vitro (Yokoyama et al., 2008) 18835274
820 livJ Campylobacter jejuni subsp. jejuni NCTC 11168 905311 218562635 Cj1019c AL111168 YP_002344414 branched-chain amino-acid ABC transporter periplasmic binding protein Virulence factor MUTATION: a Cj1019c (livJ) C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
821 cheY from Campylobacter jejuni subsp. jejuni NCTC 11168 Campylobacter jejuni subsp. jejuni NCTC 11168 905409 15792443 Cj1118c NP_282266.1 chemotaxis regulatory protein Virulence factor MUTATION: a Cj1118c (cheY) C. jejuni mutant was attenuated for the colonization of chick caeca (Hendrixson and DiRita, 2004) 15066034
822 pglF Campylobacter jejuni subsp. jejuni NCTC 11168 905411 218562734 Cj1120c AL111168 YP_002344513 UDP-GlcNAc C4,6 dehydratase Virulence factor MUTATION: a Cj1120c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
823 pglE from Campylobacter jejuni subsp. jejuni NCTC 11168 Campylobacter jejuni subsp. jejuni NCTC 11168 905412 218562735 Cj1121c HC990639 YP_002344514 UDP-4-keto-6-deoxy-GlcNAc C4 aminotransferase Virulence factor MUTATION: a cj1121c knock-out mutant is impaired for flagella-mediated motility, for invasion of intestinal epithelial cells, and for persistence in the chicken intestine (<a href="#reference11154">Vijayakumar et al., 2006</a>)
824 pglH from Campylobacter jejuni subsp. jejuni NCTC 11168 Campylobacter jejuni subsp. jejuni NCTC 11168 905420 218562743 Cj1129c AL111168 YP_002344522 GalNAc transferase/polymerase Virulence factor MUTATION: a Cj1129c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
825 fliR Campylobacter jejuni subsp. jejuni NCTC 11168 905469 218562791 Cj1179c AL111168 YP_002344570 flagellar biosynthesis protein FliR Virulence factor MUTATION: a Cj1179c C. jejuni mutant was attenuated for colonization of the chick caeca (Hendrixson and DiRita, 2004) 15066034
826 dccR Campylobacter jejuni subsp. jejuni NCTC 11168 905513 218562835 Cj1223c AL111168 YP_002344614 two-component regulator Virulence factor MUTATION: A DeltadccR (Delta Cj1223c) response regulator mutant exhibited significantly reduced colonization of immunocompetent limited flora (I-LF) mice (MacKichan et al., 2004) 15554967
827 hspR Campylobacter jejuni subsp. jejuni NCTC 11168 905521 218562842 Cj1230 AL111168 YP_002344621 heat shock transcriptional regulator Virulence factor MUTATION: hspR mutant was unable to form colonies at 44 degrees C (Andersen et al., 2005) 15758235
828 dnaJ Campylobacter jejuni subsp. jejuni NCTC 11168 905551 218562872 Cj1260c AL111168 YP_002344651 chaperone protein DnaJ Virulence factor MUTATION: a C. jejuni DnaJ mutant was unable to colonize newly hatched Leghorn chickens (Konkel et al., 1998) 9673247
829 Cj1279c Campylobacter jejuni subsp. jejuni NCTC 11168 905570 218562891 Cj1279c AL111168 YP_002344670 putative fibronectin domain-containing lipoprotein Virulence factor MUTATION: Cj1279c mutants had a significantly reduced adherence to chicken epithelial cells (Flanagan et al., 2009) 19349427
830 pseA Campylobacter jejuni subsp. jejuni NCTC 11168 905608 218562927 Cj1316c AL111168 YP_002344706 pseudaminic acid biosynthesis PseA protein Virulence factor MUTATION: Mutation of Cj1316c or pseA had been shown to result in loss of PseAm. C jejuni that produced flagella lacking PseAm failed to autoagglutinate. Mutants (81-176) defective in autoagglutination showed a modest reduction in adherence and invasion of INT407 cells (Guerry et al., 2006) 16573682
831 Cj1321 Campylobacter jejuni subsp. jejuni NCTC 11168 905613 218562932 Cj1321 AL111168 YP_002344711 putative transferase Virulence factor MUTATION: colonization of chick ceca by a Δ(Cj1321-Cj1325/6) mutant was reduced (Howard et al., 2009) 19307210
832 Cj1322 Campylobacter jejuni subsp. jejuni NCTC 11168 905614 218562933 Cj1322 AL111168 YP_002344712 hypothetical protein Virulence factor MUTATION: colonization of chick ceca by a Δ(Cj1321-Cj1325/6) mutant was reduced (<a href="#reference11121">Howard et al., 2009</a>)
833 Cj1323 Campylobacter jejuni subsp. jejuni NCTC 11168 905615 218562934 Cj1323 AL111168 YP_002344713 hypothetical protein Virulence factor MUTATION: colonization of chick ceca by a Δ(Cj1321-Cj1325/6) mutant was reduced (<a href="#reference11121">Howard et al., 2009</a>)
834 Cj1324 Campylobacter jejuni subsp. jejuni NCTC 11168 905616 218562935 Cj1324 AL111168 YP_002344714 hypothetical protein Virulence factor MUTATION: A motile ΔCj1324 mutant with intact flagella was considerably less hydrophobic, less able to autoagglutinate and form biofilms, and less able to colonize chickens than the parent strain (Howard et al., 2009) 19307210
835 Cj1325 Campylobacter jejuni subsp. jejuni NCTC 11168 905617 218562936 Cj1325 AL111168 YP_002344715 putative methyltransferase Virulence factor MUTATION: colonization of chick ceca by a Δ(Cj1321-Cj1325/6) mutant was reduced (<a href="#reference11121">Howard et al., 2009</a>)
836 Cj1326 Campylobacter jejuni subsp. jejuni NCTC 11168 905618 15792649 Cj1326 NP_282472 hypothetical protein Virulence factor MUTATION: colonization of chick ceca by a Δ(Cj1321-Cj1325/6) mutant was reduced (<a href="#reference11121">Howard et al., 2009</a>)
837 flaB Campylobacter jejuni subsp. jejuni NCTC 11168 905630 218562947 Cj1338c AL111168 YP_002344726 flagellin Virulence factor MUTATION: nonflagellated, nonmotile (flaA flaB Mot-) mutants of C. jejuni had a 30%-40% decrease in INT 407 cell internalization (<a href="#reference10977">Grant et al., 1993</a>)
838 flaA Campylobacter jejuni subsp. jejuni NCTC 11168 905631 218562948 Cj1339c AL111168 YP_002344727 flagellin Virulence factor MUTATION: nonflagellated, nonmotile (flaA flaB Mot-) mutants of C. jejuni had a 30%-40% decrease in INT 407 cell internalization (Grant et al., 1993) 8478066
839 Cj1349c Campylobacter jejuni subsp. jejuni NCTC 11168 905641 218562958 Cj1349c AL111168 YP_002344737 putative fibronectin/fibrinogen-binding protein Virulence factor MUTATION: Cj1349c mutants had a significantly reduced ability to colonize chicken epithelial cells (Flanagan et al., 2009) 19349427
840 pldA Campylobacter jejuni subsp. jejuni NCTC 11168 905643 218562960 Cj1351 AL111168 YP_002344739 phospholipase A Virulence factor MUTATION: a mutation in the pldA gene impairs the ability of C. jejuni to colonize the cecum (Ziprin et al., 2001) 11569726
841 Cj1461 Campylobacter jejuni subsp. jejuni NCTC 11168 905749 218563064 Cj1461 AL111168 YP_002344843 putative DNA methylase Virulence factor MUTATION: A Deltacj1461 mutant was sevenfold more adherent to but 50-fold less invasive of INT-407 human epithelial cells than the wild type (Kim et al., 2008) 18689478
842 flgK Campylobacter jejuni subsp. jejuni NCTC 11168 905754 218563069 Cj1466 AL111168 YP_002344848 flagellar hook-associated protein FlgK Virulence factor MUTATION: a flgK mutant of C. jejuni expressing only the hook filament junction protein showed diminished motility and was completely attenuated for cecal colonization in chickens (Fernando et al., 2007) 17761334
843 pflA Campylobacter jejuni subsp. jejuni NCTC 11168 905864 218563154 Cj1565c AL111168 YP_002344934 paralysed flagellum protein Virulence factor MUTATION: a Cj1565c C. jejuni mutant was attenuated for colonization of the chick caeca
844 sdaA Campylobacter jejuni subsp. jejuni NCTC 11168 905896 218563213 Cj1624c AL111168 YP_002344993 L-serine dehydratase Virulence factor MUTATION: sdaA mutants completely failed to colonize 3-week-old chickens as assayed both by cloacal swabs taken over a 6-week period and by cecal colony counts postmortem (Velayudhan et al., 2004) 14688104
845 peb1A Campylobacter jejuni subsp. jejuni NCTC 11168 906008 218562540 Cj0921c AL111168 YP_002344319 bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein Virulence factor MUTATION: reduced adherence to epithelial cells, attenuated in mice (Pei et al., 1998). 9488379
846 ciaB from Campylobacter jejuni RM1221 Campylobacter jejuni RM1221 3231503 57237742 CJE0992 YP_178990.1 invasion antigen B Virulence factor MUTATION: C. jejuni ciaB null mutants had a significant reduction in internalization (<a href="#reference10922">Konkel et al., 1999</a>)
847 CJE0997 Campylobacter jejuni RM1221 3231508 57237747 CJE0997 CP000025 YP_178995 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEP1 mutants had a significantly reduced in vivo colonization of broiler chicks (Flanagan et al., 2009) 19349427
848 CJE0998 Campylobacter jejuni RM1221 3231509 57237748 CJE0998 CP000025 YP_178996 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chicks (Flanagan et al., 2009) 19349427
849 pebC from Campylobacter jejuni RM1221 Campylobacter jejuni RM1221 3231511 57237750 CJE1000 YP_178998.1 amino acid ABC transporter, ATP-binding protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colinization of broiler chickens (Flanagan et al., 2009) 19349427
850 jlpA from Campylobacter jejuni RM1221 Campylobacter jejuni RM1221 3231574 57237810 CJE1065 YP_179058.1 surface-exposed lipoprotein Virulence factor MUTATION: adherence of deletion mutants of jlpA to HEp-2 epithelial cells was reduced compared with that of parental C. jejuni (Jin et al., 2001) 11251839
851 pglH from Campylobacter jejuni RM1221 Campylobacter jejuni RM1221 3231778 57238010 CJE1271 YP_179259.1 general glycosylation pathway protein Virulence factor MUTATION: reduce ability to adhere to human epithelial Caco-2 cells (Karlyshev et al., 2004). 15184581
1688 pebC from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4682094 121612723 CJJ81176_0929 YP_001000596.1 amino acid ABC transporter, ATP-binding protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1689 motB from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4682104 121612816 CJJ81176_0358 YP_001000046.1 flagellar motor protein MotB Virulence factor MUTATION: A motB insertion-deletion mutant failed to establish colonization in LF mice (Chang and Miller, 2006) 16926420
1690 cheY from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4682456 121613202 CJJ81176_1136 YP_001000796.1 chemotaxis protein CheY Virulence factor MUTATION: Insertional inactivation of the cheY gene in 81-176 resulted in an approx. threefold increase in adherence and invasion in vitro, but this strain was unable to colonize or cause disease in animals (Yao et al., 1997) 9076738
1691 cheA Campylobacter jejuni subsp. jejuni 81-176 4682610 121613274 CJJ81176_0310 CP000538 YP_999998 chemotaxis protein CheA Virulence factor MUTATION: A cheA insertion-deletion mutant failed to establish colonization in LF mice (Chang and Miller, 2006) 16926420
1692 jlpA from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4682683 121613448 CJJ81176_1002 YP_001000663.1 surface-exposed lipoprotein Virulence factor MUTATION: adherence of deletion mutants of jlpA to HEp-2 epithelial cells was reduced compared with that of parental C. jejuni (Jin et al., 2001) 11251839
1693 ciaB from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4682759 121612338 CJJ81176_0921 YP_001000588.1 invasion antigen B Virulence factor MUTATION: C. jejuni ciaB null mutants had a significant reduction in internalization (<a href="#reference10922">Konkel et al., 1999</a>)
1694 pglB Campylobacter jejuni subsp. jejuni 81-176 4682880 121612188 CJJ81176_1143 NZ_AASL01000001 YP_001000803 general glycosylation pathway protein Virulence factor MUTATION: pglB impaired in glycosylation showed reduced ability to adhere to INT407 cells and colonize in mice (Szymanski et al., 2002). 11895996
1695 CJJ81176_0927 Campylobacter jejuni subsp. jejuni 81-176 4683249 121612211 CJJ81176_0927 NZ_AASL01000001 YP_001000594 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1696 kpsC Campylobacter jejuni subsp. jejuni 81-176 4683284 121612738 CJJ81176_1413 NZ_AASL01000001 YP_001001069 capsule polysaccharide export protein KpsC Virulence factor MUTATION: kpsC mutants were defective in colonization and virulence (Grant et al., 2005) 16332783
1697 CJJ81176_1165 Campylobacter jejuni subsp. jejuni 81-176 4683357 121613507 CJJ81176_1165 AY423899 YP_001000825 LPS glycosyltransferase subfamily protein Virulence factor MUTATION: knockout strains showed reduced ability to invade epithelial cells (Louwen et al., 2008). 18644887
1698 fliI Campylobacter jejuni subsp. jejuni 81-176 4683388 121613240 CJJ81176_0226 NZ_AASL01000001 YP_999914 flagellum-specific ATP synthase Virulence factor MUTATION: A flil insertion-deletion mutant failed to establish colonization in LF mice (Chang and Miller, 2006) 16926420
1699 ggt from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4683465 121613257 CJJ81176_0067 YP_999755.1 gamma-glutamyltransferase Virulence factor MUTATION: mutations in ggt showed it to be required for persistent colonization of the avian gut (Barnes et al., 2007) 17600669
1700 cadF Campylobacter jejuni subsp. jejuni 81-176 4683585 121612147 CJJ81176_1471 NZ_AASL01000001 YP_001001127 fibronectin-binding protein Virulence factor MUTATION: cadF mutants had reduced binding to immobilized Fn as compared to wt strains (Monteville et al., 2003) 12576589
1701 pglH from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4683595 121613657 CJJ81176_1146 YP_001000806.1 general glycosylation pathway protein Virulence factor MUTATION: reduce ability to adhere to human epithelial Caco-2 cells (Karlyshev et al., 2004). 15184581
1702 CJJ81176_0926 Campylobacter jejuni subsp. jejuni 81-176 4683648 121613743 CJJ81176_0926 NZ_AASL01000001 YP_001000593 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1703 pglE from Campylobacter jejuni subsp. jejuni 81-176 Campylobacter jejuni subsp. jejuni 81-176 4683652 121612710 CJJ81176_1139 AF108897 YP_001000799 general glycosylation pathway protein Virulence factor MUTATION: knockout mutant impaired for flagella-mediated motility and invasion of intestinal epithelial cells (Vijayakumar et al., 2006). 16690622
1779 JJD26997_0895 Campylobacter jejuni subsp. doylei 269.97 5388635 153952480 JJD26997_0895 CP000768 YP_001398011 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1780 jlpA from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5388922 153952037 JJD26997_0805 YP_001397934.1 surface-exposed lipoprotein Virulence factor MUTATION: adherence of deletion mutants of jlpA to HEp-2 epithelial cells was reduced compared with that of parental C. jejuni (Jin et al., 2001) 11251839
1781 pebC from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5389528 153951397 JJD26997_0892 YP_001398008.1 amino acid ABC transporter, ATP-binding protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1782 pebA from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5389725 153952077 JJD26997_0893 YP_001398009.1 amino acid ABC transporter, periplasmic amino acid-binding protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1783 ciaB from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5390001 153952319 JJD26997_0900 YP_001398016.1 invasion antigen B Virulence factor MUTATION: C. jejuni ciaB null mutants had a significant reduction in internalization (<a href="#reference10922">Konkel et al., 1999</a>)
1784 JJD26997_0894 Campylobacter jejuni subsp. doylei 269.97 5390171 153951698 JJD26997_0894 CP000768 YP_001398010 amino acid ABC transporter, permease protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
1785 ggt from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5390397 153951153 JJD26997_0042 YP_001397302.1 gamma-glutamyltransferase Virulence factor MUTATION: mutations in ggt showed it to be required for persistent colonization of the avian gut (<a href="#reference11135">Barnes et al., 2007</a>)
1786 pglH from Campylobacter jejuni subsp. doylei 269.97 Campylobacter jejuni subsp. doylei 269.97 5390593 153951965 JJD26997_0592 YP_001397761.1 general glycosylation pathway protein Virulence factor MUTATION: reduce ability to adhere to human epithelial Caco-2 cells (Karlyshev et al., 2004). 15184581
1842 racR Campylobacter jejuni subsp. jejuni 81116 5617154 157415525 C8J_1205 CP000814 YP_001482781 DNA-binding response regulator Virulence factor MUTATION: A mutation of the response regulator gene racR reduced the organism's ability to colonize the chicken intestinal tract (Brás et al., 1999) 10322038
1843 C8J_0850 Campylobacter jejuni subsp. jejuni 81116 5617830 157415170 C8J_0850 CP000814 YP_001482426 invasion antigen B Virulence factor MUTATION: C. jejuni ciaB null mutants had a significant reduction in internalization (<a href="#reference10922">Konkel et al., 1999</a>)
1844 pebA from Campylobacter jejuni subsp. jejuni 81116 Campylobacter jejuni subsp. jejuni 81116 5618176 157415178 C8J_0858 YP_001482434.1 amino acid ABC transporter, periplasmic amino acid-binding protein PEB1 Virulence factor MUTATION: PEB1 mutants had a significantly reduced in vivo colonization of broiler chickens (Flanagan et al., 2009) 19349427
4871 LPS Campylobacter jejuni Virulence factor MUTATION: A galE mutant which expressed a lipid A-core molecule of reduced molecular weight that did not react with antiserum raised against the parental strain. The galE mutant also showed a reduction in its ability to adhere to and invade INT407 cells (Fry et al., 2000). 10768949
4874 kpsM Campylobacter jejuni subsp. jejuni 81-176 4683743 121613575 CJJ81176_1441 CP000538 YP_001001097 capsular polysaccharide ABC transporter, permease protein Virulence factor MUTATION: kpsM mutant is significantly reduced in invasion of INT407 cells and reduced in virulence in a ferret diarrhoeal disease model (Bacon et al., 2001). 11359581
4875 kpsE Campylobacter jejuni subsp. jejuni 81116 5617759 157415671 C8J_1352 CP000814 YP_001482927 capsular polysaccharide ABC transporter Virulence factor MUTATION: the capacity of a kpsE mutant to adhere to the INT-407 cells was reduced 20-fold, and the invasion capability of the kpsE mutant was two-fold lower than that of the wild type (Bachtiar et al., 2007). 17266722