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Found 175 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
2878 aroE from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5794959 161870711 NMCC_1783 YP_001599884.1 shikimate dehydrogenase Virulence factor MUTATION: aroE mutant is attenuated in rats (Sun et al., 2000). 11062540
2879 rfaK from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5794989 161870550 NMCC_1616 YP_001599722.1 alpha 1,2 N-acetylglucosamine transferase Virulence factor MUTATION: rfaK mutant is attenuated in rats (Sun et al., 2000). 11062540
2880 metF from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795024 161869855 NMCC_0886 YP_001599024.1 5,10-methylenetetrahydrofolate reductase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
2881 rnc from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795078 161869625 NMCC_0642 YP_001598793.1 ribonuclease III Virulence factor MUTATION: rnc mutant is attenuated in rats (Sun et al., 2000). 11062540
2882 fhs from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795151 161869376 NMCC_0383 YP_001598543.1 formate--tetrahydrofolate ligase Virulence factor MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000). 11062540
2883 pilX from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795172 161869822 NMCC_0851 YP_001598991.1 type IV pilus assembly protein PilX Virulence factor MUTATION: pilX mutant has reduced adherence to human epithelial cells (Hélaine et al., 2005). 15612917
2884 gdhA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795290 161870555 NMCC_1621 YP_001599727.1 glutamate dehydrogenase Virulence factor MUTATION: gdhA mutant is attenuated in rats (Sun et al., 2000). 11062540
2885 rfaF from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795358 161870387 NMCC_1433 YP_001599559.1 ADP-heptose:LPS heptosyltransferase II Virulence factor MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000). 11062540
2886 fba from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795400 161869346 NMCC_0352 YP_001598513.1 fructose-1,6-bisphosphate aldolase Virulence factor MUTATION: fba mutant is attenuated in rats (Sun et al., 2000). 11062540
2887 ptsI from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795401 161869148 NMCC_0142 YP_001598314.1 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: ptsI mutant is attenuated in rats (Sun et al., 2000). 11062540
2888 grxC from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795405 161869428 NMCC_0436 YP_001598595.1 glutaredoxin 3 Virulence factor MUTATION: grxC mutant is attenuated in rats (Sun et al., 2000). 11062540
2889 rsmB from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795455 161870942 NMCC_2036 YP_001600122.1 16S RNA methyltransferase Virulence factor MUTATION: rsmB mutant is attenuated in rats (Sun et al., 2000). 11062540
2890 pbp3 Neisseria meningitidis 053442 5795502 161869423 NMCC_0431 YP_001598590.1 Penicillin-binding protein 3 Virulence factor MUTATION: pbp3 mutant is attenuated in rats (Sun et al., 2000). 11062540
2891 ilvI from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795606 161870432 NMCC_1480 YP_001599604.1 acetolactate synthase isozyme III large subunit Virulence factor MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000). 11062540
2892 aroB from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795648 161869406 NMCC_0414 YP_001598573.1 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000). 11062540
2893 lipB from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795650 161869101 NMCC_0091 YP_001598267.1 capsule polysaccharide modification protein Virulence factor MUTATION: lipB mutant is attenuated in rats (Sun et al., 2000). 11062540
2894 pnp from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795721 161869702 NMCC_0722 YP_001598869.1 polyribonucleotide nucleotidyltransferase Virulence factor MUTATION: pnp mutant is attenuated in rats (Sun et al., 2000). 11062540
2895 pilQ from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795870 161869408 NMCC_0416 YP_001598575.1 type IV pilus assembly protein PilQ Virulence factor MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2896 aroC from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795881 161870528 NMCC_1593 YP_001599700.1 chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in rats (Sun et al., 2000). 11062540
2897 purL from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5795982 161869205 NMCC_0209 YP_001598371.1 phophoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Sun et al., 2000). 11062540
2898 ilvD from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796004 161870035 NMCC_1068 YP_001599204.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000). 11062540
2899 tonB from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796129 161870577 NMCC_1643 YP_001599749.1 TonB protein Virulence factor MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002). 11854233
2900 ampD from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796140 161869605 NMCC_0621 YP_001598772.1 anhydro-N-acetylmuramyl-tripeptide amidase Virulence factor MUTATION: ampD mutant is attenuated in rats (Sun et al., 2000). 11062540
2901 rfaE from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796145 161869766 NMCC_0786 YP_001598933.1 ADP-heptose synthetase Virulence factor MUTATION: rfaE mutant is attenuated in rats (Sun et al., 2000). 11062540
2902 pilF from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796169 161870741 NMCC_1814 YP_001599914.1 type IV pilus assembly protein Virulence factor MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2903 metG from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796183 161869048 NMCC_0031 YP_001598214.1 methionyl-tRNA synthetase Virulence factor MUTATION: metG mutant is attenuated in rats (Sun et al., 2000). 11062540
2904 ptsH from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796187 161869147 NMCC_0141 YP_001598313.1 sugar transport PTS system phosphocarrier protein HPR Virulence factor MUTATION: ptsH mutant is attenuated in rats (Sun et al., 2000). 11062540
2905 dprA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796233 161870938 NMCC_2032 YP_001600118.1 DNA processing chain A Virulence factor MUTATION: dprA mutant is attenuated in rats (Sun et al., 2000). 11062540
2906 ntrY Neisseria meningitidis 053442 5796235 161870940 NMCC_2034 YP_001600120.1 nitrogen regulation protein NtrY, putative Virulence factor MUTATION: ntrY mutant is attenuated in rats (Sun et al., 2000). 11062540
2907 aroD from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796331 161870315 NMCC_1357 YP_001599485.1 3-dehydroquinate dehydratase Virulence factor MUTATION: aroD mutant is attenuated in rats (Sun et al., 2000). 11062540
2908 lgtA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796357 161869284 NMCC_0289 YP_001598451.1 lacto-N-neotetraose biosynthesis glycosyl tranferase Virulence factor MUTATION: lgtA mutant is attenuated in rats (Sun et al., 2000). 11062540
2909 dedA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796649 161870537 NMCC_1602 YP_001599709.1 putative DedA protein Virulence factor MUTATATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
2910 exbD from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796685 161870575 NMCC_1641 YP_001599747.1 biopolymer transport protein Virulence factor MUTATION: exbD mutant is attenuated in rats (Sun et al., 2000). 11062540
2911 exbB from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796686 161870576 NMCC_1642 YP_001599748.1 biopolymer transport protein Virulence factor MUTATION: exbB mutant is attenuated in rats (Sun et al., 2000). 11062540
2912 dedA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796698 161869935 NMCC_0967 YP_001599104.1 putative DedA protein Virulence factor MUTATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
2913 opcA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796699 161869936 NMCC_0968 YP_001599105.1 outer membrane protein precursor Virulence factor Bacteria expressing low or undetectable levels of Opc protein failed to adhere to or invade eukaryotic cells (Virji et al., 1992). 1435257
2914 hmbR from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796721 0 NMCC_1579 - hemoglobin receptor Virulence factor MUTATION: hmbR mutant was attenuated in an infant rat model (Stojiljkovic et al., 1995). 7783623
2915 siaD Neisseria meningitidis 053442 5796762 161869086 NMCC_0075 YP_001598252.1 alpha-2,8 polysialyltransferase Virulence factor MUTATION: siaD mutant is attenuated in rats (Sun et al., 2000). 11062540
2916 nadA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796858 161870678 NMCC_1750 YP_001599851.1 quinolinate synthetase A Virulence factor MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009). 19481311
2917 galU from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796882 161869571 NMCC_0586 YP_001598738.1 UTP--glucose-1-phosphate uridylyltransferase Virulence factor MUTATION: galU mutant is attenuated in rats (Sun et al., 2000). 11062540
2918 hrpA from Neisseria meningitidis 053442 Neisseria meningitidis 053442 5796971 161869191 NMCC_0194 YP_001598357.1 ATP-dependent RNA helicase HrpA Virulence factor MUTATION: hrpA mutants are deficient in the ability to live/grow in HeLa cells (Talà et al., 2008). 18680551
2919 aroB from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4674848 121634271 NMC0406 YP_974516.1 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000). 11062540
2920 fba from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4674894 121634217 NMC0350 YP_974462.1 fructose-1,6-bisphosphate aldolase Virulence factor MUTATION: fba mutant is attenuated in rats (Sun et al., 2000). 11062540
2921 rfaF from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675030 121635198 NMC1456 YP_975443.1 ADP-heptose:LPS heptosyltransferase II Virulence factor MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000). 11062540
2922 metG from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675118 121633907 NMC0007 YP_974152.1 methionyl-tRNA synthetase Virulence factor MUTATION: metG mutant is attenuated in rats (Sun et al., 2000). 11062540
2923 aroC from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675192 121635321 NMC1598 YP_975566.1 chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in rats (Sun et al., 2000). 11062540
2924 gdhA from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675196 121635346 NMC1625 YP_975591.1 glutamate dehydrogenase Virulence factor MUTATION: gdhA mutant is attenuated in rats (Sun et al., 2000). 11062540
2925 metF from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675430 121634746 NMC0921 YP_974991.1 5,10-methylenetetrahydrofolate reductase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
2926 ampD from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675580 121634464 NMC0617 YP_974709.1 N-acetyl-anhydromuranmyl-L-alanine amidase Virulence factor MUTATION: ampD mutant is attenuated in rats (Sun et al., 2000). 11062540
2927 rnc from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675618 121634484 NMC0637 YP_974729.1 ribonuclease III Virulence factor MUTATION: rnc mutant is attenuated in rats (Sun et al., 2000). 11062540
2928 pilQ from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675619 121634273 NMC0408 YP_974518.1 pilus secretin Virulence factor MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2929 aroD from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675764 121635135 NMC1383 YP_975380.1 3-dehydroquinate dehydratase Virulence factor MUTATION: aroD mutant is attenuated in rats (Sun et al., 2000). 11062540
2930 exbB from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675875 121635363 NMC1649 YP_975608.1 biopolymer transport protein Virulence factor MUTATION: exbB mutant is attenuated in rats (Sun et al., 2000). 11062540
2931 tonB from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675898 121635364 NMC1650 YP_975609.1 TonB protein Virulence factor MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002). 11854233
2932 ilvD from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675932 121634888 NMC1090 YP_975133.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000). 11062540
2933 lgtA from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4675978 121635586 NMC1902 YP_975831.1 lacto-N-neotetraose biosynthesis glycosyl tranferase Virulence factor MUTATION: lgtA mutant is attenuated in rats (Sun et al., 2000). 11062540
2934 ptsH from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676011 121635703 NMC2025 YP_975948.1 sugar transport PTS system phosphocarrier protein HPR Virulence factor MUTATION: ptsH mutant is attenuated in rats (Sun et al., 2000). 11062540
2935 pilF from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676178 121635535 NMC1844 YP_975780.1 type IV pilus assembly protein Virulence factor MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2936 dedA from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676301 121634825 NMC1016 YP_975070.1 DedA protein ortholog Virulence factor MUTATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
2937 nadA from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676346 121635470 NMC1772 YP_975715.1 quinolinate synthetase Virulence factor MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009). 19481311
2938 rfaK from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676380 121635341 NMC1619 YP_975586.1 alpha 1,2 N-acetylglucosamine transferase Virulence factor MUTATION: rfaK mutant is attenuated in rats (Sun et al., 2000). 11062540
2939 lipB from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676394 121633961 NMC0067 YP_974206.1 capsule polysaccharide modification protein Virulence factor MUTATION: lipB mutant is attenuated in rats (Sun et al., 2000). 11062540
2940 ilvI from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676427 121635234 NMC1497 YP_975479.1 acetolactate synthase isozyme III large subunit Virulence factor MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000). 11062540
2941 ptsI from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676530 121635702 NMC2024 YP_975947.1 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: ptsI mutant is attenuated in rats (Sun et al., 2000). 11062540
2942 aroE Neisseria meningitidis FAM18 from Neisseria meningitidis FAM18 4676581 121635506 NMC1810 YP_975751.1 shikimate dehydrogenase Virulence factor MUTATION: aroE mutant is attenuated in rats (Sun et al., 2000). 11062540
2943 purL from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676582 121635654 NMC1972 YP_975899.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Sun et al., 2000). 11062540
2944 mltB from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676597 121634994 NMC1212 YP_975239.1 murein hydrolase Virulence factor MUTATION: mltB mutant is attenuated in rats (Sun et al., 2000). 11062540
2945 exbD from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676643 121635362 NMC1648 YP_975607.1 biopolymer transport protein Virulence factor MUTATION: exbD mutant is attenuated in rats (Sun et al., 2000). 11062540
2946 aroG from Neisseria meningitidis FAM18 Neisseria meningitidis FAM18 4676702 121635563 NMC1874 YP_975808.1 phospho-2-dehydro-3-heoxyheptonate aldolase Virulence factor MUTATION: aroG mutant is attenuated in rats (Sun et al., 2000). 11062540
2947 lipB from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906200 15793213 NMA0185 NP_283035.1 capsule polysaccharide modification protein Virulence factor MUTATION: lipB mutant is attenuated in rats (Sun et al., 2000). 11062540
2948 metG from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906284 15793293 NMA0275 NP_283115.1 methionyl-tRNA synthetase Virulence factor MUTATION: metG mutant is attenuated in rats (Sun et al., 2000). 11062540
2949 ptsH from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906394 15793399 NMA0391 NP_283221.1 sugar transport PTS system phosphocarrier protein HPR Virulence factor MUTATION: ptsH mutant is attenuated in rats (Sun et al., 2000). 11062540
2950 ptsI from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906395 15793400 NMA0392 NP_283222.1 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: ptsI mutant is attenuated in rats (Sun et al., 2000). 11062540
2951 purL from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906445 15793449 NMA0445 NP_283271.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Sun et al., 2000). 11062540
2952 lgtA from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906518 15793522 NMA0524 NP_283344.1 lacto-N-neotetraose biosynthesis glycosyl tranferase Virulence factor MUTATION: lgtA mutant is attenuated in rats (Sun et al., 2000). 11062540
2953 fba from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906580 15793578 NMA0587 NP_283400.1 fructose-1,6-bisphosphate aldolase Virulence factor MUTATION: fba mutant is attenuated in rats (Sun et al., 2000). 11062540
2954 fhs from Neisseria meningitidis Z2491 N eisseria meningitidis Z2491 906612 15793607 NMA0617 NP_283429.1 formate--tetrahydrofolate ligase Virulence factor MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000) 11062540
2955 aroB from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906642 15793633 NMA0647 NP_283455.1 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000). 11062540
2956 pilQ from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906644 15793635 NMA0650 NP_283457.1 pilus secretin Virulence factor MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2957 NMA0798 Neisseria meningitidis Z2491 906788 15793772 NMA0798 NP_283594.1 two-component system regulator Virulence factor MUTATION: NMA0798 (phoP) mutant is avirulent in mice (Newcombe et al., 2004). 14688113
2958 galU from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906836 15793818 NMA0848 NP_283640.1 UTP--glucose-1-phosphate uridylyltransferase Virulence factor MUTATION: galU mutant is attenuated in rats (Sun et al., 2000). 11062540
2959 ampD from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906854 15793836 NMA0867 NP_283658.1 N-acetyl-anhydromuranmyl-L-alanine amidase Virulence factor MUTATION: ampD mutant is attenuated in rats (Sun et al., 2000). 11062540
2960 rnc from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 906875 15793857 NMA0888 NP_283679.1 ribonuclease III Virulence factor MUTATION: rnc mutant is attenuated in rats (Sun et al., 2000). 11062540
2961 rfaE from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907010 15793990 NMA1034 NP_283812.1 DP-heptose synthetase Virulence factor MUTATION: rfaE mutant is attenuated in rats (Sun et al., 2000). 11062540
2962 metF from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907108 15794085 NMA1139 NP_283907.1 5,10-methylenetetrahydrofolate reductase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
2963 gdhA from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907187 15794847 NMA1964 NP_284669.1 glutamate dehydrogenase Virulence factor MUTATION: gdhA mutant is attenuated in rats (Sun et al., 2000). 11062540
2964 aroG from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907267 15795051 NMA2180 NP_284873.1 phospho-2-dehydro-3-heoxyheptonate aldolase Virulence factor MUTATION: aroG mutant is attenuated in rats (Sun et al., 2000). 11062540
2965 pilF from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907288 15795030 NMA2159 NP_284852.1 type IV pilus assembly protein Virulence factor MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2966 aroE from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907318 15795000 NMA2129 NP_284822.1 shikimate dehydrogenase Virulence factor MUTATION: aroE mutant is attenuated in rats (Sun et al., 2000). 11062540
2967 nadA from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907353 15794965 NMA2090 NP_284787.1 quinolinate synthetase Virulence factor MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009). 19481311
2968 tonB Neisseria meningitidis 907455 15794867 NMA1985 NP_284689.1 TonB protein Virulence factor MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002). 11854233
2969 exbD from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907458 15794865 NMA1983 NP_284687.1 biopolymer transport protein Virulence factor MUTATION: exbD mutant is attenuated in rats (Sun et al., 2000). 11062540
2970 exbB from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907459 15794866 NMA1984 NP_284688.1 biopolymer transport protein Virulence factor MUTATION: exbB mutant is attenuated in rats (Sun et al., 2000). 11062540
2971 rfaK from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907476 15794842 NMA1959 NP_284664.1 alpha 1,2 N-acetylglucosamine transferase Virulence factor MUTATION: rfaK mutant is attenuated in rats (Sun et al., 2000). 11062540
2972 aroC from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907493 15794822 NMA1939 NP_284644.1 chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in rats (Sun et al., 2000). 11062540
2973 dedA from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907554 15794185 NMA1250 NP_284007.1 DedA protein ortholog Virulence factor MUTATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
2974 opcA from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907555 15794186 NMA1251 NP_284008.1 outer membrane protein precursor Virulence factor Bacteria expressing low or undetectable levels of Opc protein failed to adhere to or invade eukaryotic cells (Virji et al., 1992). 1435257
2975 ilvI from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907658 15794659 NMA1766 NP_284481.1 acetolactate synthase isozyme III large subunit Virulence factor MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000). 11062540
2976 ilvD from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907768 15794282 NMA1361 NP_284104.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000). 11062540
2977 mltB from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 907882 15794388 NMA1488 NP_284210.1 murein hydrolase Virulence factor MUTATION: mltB mutant is attenuated in rats (Sun et al., 2000).
11062540
2978 aroD from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 908048 15794553 NMA1659 NP_284375.1 3-dehydroquinate dehydratase Virulence factor MUTATION: aroD mutant is attenuated in rats (Sun et al., 2000). 11062540
2979 rfaF from Neisseria meningitidis Z2491 Neisseria meningitidis Z2491 908116 15794620 NMA1727 NP_284442.1 ADP-heptose:LPS heptosyltransferase II Virulence factor MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000). 11062540
2980 metG from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902133 15675970 NMB0030 NP_273096.1 methionyl-tRNA synthetase Virulence factor MUTATION: metG mutant is attenuated in rats (Sun et al., 2000). 11062540
2981 lipB from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902187 15676016 NMB0083 NP_273146.1 capsule polysaccharide modification protein LipB Virulence factor MUTATION: lipB mutant is attenuated in rats (Sun et al., 2000). 11062540
2982 NMB0103 Neisseria meningitidis MC58 902207 15676031 NMB0103 NP_273161.1 putative bacteriocin resistance protein Virulence factor MUTATION: NMB0103 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2983 rsmB from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902216 15676040 NMB0112 NP_273170.1 16S RNA methyltransferase Virulence factor MUTATION: rsmB mutant is attenuated in rats (Sun et al., 2000). 11062540
2984 dprA from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902220 15676044 NMB0116 NP_273174.1 DNA processing chain A Virulence factor MUTATION: dprA mutant is attenuated in rats (Sun et al., 2000). 11062540
2985 tufA Neisseria meningitidis MC58 902247 15676067 NMB0139 NP_273197.1 elongation factor Tu Virulence factor MUTATION: tufA mutant is attenuated in rats (Sun et al., 2000). 11062540
2986 lpxA Neisseria meningitidis MC58 902285 15676105 NMB0178 NP_273236.1 UDP-N-acetylglucosamine acyltransferase Virulence factor MUTATION: lpxA mutant is attenuated in mice (Zarantonelli et al., 2006). 16988225
2987 aroG from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902423 15676225 NMB0307 NP_273357.1 phospho-2-dehydro-3-heoxyheptonate aldolase Virulence factor MUTATION: aroG mutant is attenuated in rats (Sun et al., 2000). 11062540
2988 NMB0313 Neisseria meningitidis MC58 902429 15676230 NMB0313 NP_273362.1 hypothetical protein Virulence factor MUTATION: NMB0313 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2989 pilF from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902445 15676245 NMB0329 NP_273378.1 type IV pilus assembly protein Virulence factor MUTATION: pilF mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2990 aroE from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902474 15676273 NMB0358 NP_273407.1 shikimate 5-dehydrogenase Virulence factor MUTATION: aroE mutant is attenuated in rats (Sun et al., 2000). 11062540
2991 nadA from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902509 15676308 NMB0394 NP_273443.1 quinolinate synthetase Virulence factor MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009). 19481311
2992 NMB0541 Neisseria meningitidis MC58 902656 15676447 NMB0541 NP_273586.1 hypothetical protein Virulence factor MUTATION: NMB0541 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
2993 galU from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902749 15676538 NMB0638 NP_273681.1 UTP--glucose-1-phosphate uridylyltransferase Virulence factor MUTATION: galU mutant is attenuated in rats (Sun et al., 2000). 11062540
2994 ampD from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902779 15676566 NMB0668 NP_273710.1 N-acetyl-anhydromuranmyl-L-alanine amidase Virulence factor MUTATION: ampD mutant is attenuated in rats (Sun et al., 2000). 11062540
2995 rnc from Neisseria meningitidis MC58 Neisseria meningitidis MC58 902798 15676584 NMB0686 NP_273728.1 ribonuclease III Virulence factor MUTATION: rnc mutant is attenuated in rats (Sun et al., 2000). 11062540
2996 hfq Neisseria meningitidis MC58 902863 15676646 NMB0748 NP_273790.1 host factor-I Virulence factor MUTATION: hfq mutant is attenuated in rats (Fantappiè et al., 2009). 19223479
2997 pgm Neisseria meningitidis MC58 902905 15676688 NMB0790 NP_273832.1 phosphoglucomutase Virulence factor MUTATION: pgm mutant is attenuated in mice (Plant et al., 2006). 16428785
2998 rfaD Neisseria meningitidis MC58 902942 15676725 NMB0828 NP_273870.1 ADP-L-glycero-D-mannoheptose-6-epimerase Virulence factor MUTATION: rfaD mutant is attenuated in mice (Zarantonelli et al., 2006). 16988225
2999 metF from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903063 15676836 NMB0943 NP_273981.1 5,10-methylenetetrahydrofolate reductase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
3000 metH Neisseria meningitidis MC58 903064 15676837 NMB0944 NP_273982.1 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
3001 pilQ from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903122 15678016 NMB1812 NP_274809.1 pilQ protein Virulence factor MUTATION: pilQ mutant were unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
3002 NMB1012 Neisseria meningitidis MC58 903150 15676901 NMB1012 NP_274047.1 hypothetical protein Virulence factor MUTATION: NMB1012 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
3003 dedA from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903189 15676938 NMB1052 NP_274086.1 dedA protein Virulence factor MUTATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
3004 opc Neisseria meningitidis MC58 903235 15676939 NMB1053 NP_274087.1 class 5 outer membrane protein Virulence factor Bacteria expressing low or undetectable levels of Opc protein failed to adhere to or invade eukaryotic cells (Virji et al., 1992). 1435257
3005 fhs from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903260 15677675 NMB1839 NP_274836.1 formate--tetrahydrofolate ligase Virulence factor MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000).
11062540
3006 NMB1829 Neisseria meningitidis MC58 903271 15677665 NMB1829 NP_274826.1 TonB-dependent receptor Virulence factor MUTATION: NMB1829 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
3007 aroB from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903286 15677650 NMB1814 NP_274811.1 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000). 11062540
3008 grxC from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903309 15677630 NMB1790 NP_274789.1 glutaredoxin 3 Virulence factor MUTATION: grxC mutant is attenuated in rats (Sun et al., 2000). 11062540
3009 tonB from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903369 15677576 NMB1730 NP_274733.1 TonB protein Virulence factor MUTATION: tonB mutant is unable to replicate within human epithelial cells (Larson et al., 2002). 11854233
3010 exbB from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903370 15677575 NMB1729 NP_274732.1 biopolymer transport protein ExbB Virulence factor MUTATION: exbB mutant is attenuated in rats (Sun et al., 2000). 11062540
3011 exbD from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903371 15677574 NMB1728 NP_274731.1 biopolymer transport protein ExbD Virulence factor MUTATION: exbD mutant is attenuated in rats (Sun et al., 2000). 11062540
3012 NMB1726 N eisseria meningitidis MC58 903375 15677572 NMB1726 NP_274729.1 hypothetical protein Virulence factor MUTATION: NMB1726 mutant was unable to colonize human nasopharyngeal tissue in an organ culture model (Exley et al., 2009). 18936183
3013 gdhA from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903392 15677557 NMB1710 NP_274713.1 glutamate dehydrogenase Virulence factor MUTATION: gdhA mutant is attenuated in rats (Sun et al., 2000). 11062540
3014 rfaK from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903397 15677553 NMB1705 NP_274709.1 alpha-1,2-N-acetylglucosamine transferase Virulence factor MUTATION: rfaK mutant is attenuated in rats (Sun et al., 2000). 11062540
3015 aroC from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903428 15677528 NMB1680 NP_274684.1 chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in rats (Sun et al., 2000). 11062540
3016 hmbR from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903442 15677517 NMB1668 NP_274673.1 hemoglobin receptor Virulence factor MUTATION: hmbR mutant was attenuated in an infant rat model (Stojiljkovic et al., 1995). 7783623
3017 mpl-1 Neisseria meningitidis MC58 903566 15677021 NMB1145 NP_274173.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Virulence factor MUTATION: mpl-1 mutant is attenuated in rats (Sun et al., 2000). 11062540
3018 aroD from Neisseria meningitidis MC58 Neisseria meningitidis MC58 903866 15677303 NMB1446 NP_274458.1 3-dehydroquinate dehydratase Virulence factor MUTATION: aroD mutant is attenuated in rats (Sun et al., 2000). 11062540
3019 NMB1638 Neisseria meningitidis MC58 903951 15677487 NMB1638 NP_274643.1 YhbX/YhjW/YijP/YjdB family protein Virulence factor MUTATION: MNB1638 (lptA) mutant had an approximately 10-fold decrease in N. meningitidis adhesion to four kinds of human endothelial and epithelial cell lines at an multiplicity of infection of 5,000 (Takahashi et al., 2008). 18824535
3020 rfaF from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904029 15677379 NMB1527 NP_274534.1 ADP-heptose--LPS heptosyltransferase II Virulence factor MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000). 11062540
3021 ptsH from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904045 15677867 NMB2045 NP_275035.1 phosphocarrier protein HPr Virulence factor MUTATION: ptsH mutant is attenuated in rats (Sun et al., 2000). 11062540
3022 ptsI from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904047 15677866 NMB2044 NP_275034.1 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: ptsI mutant is attenuated in rats (Sun et al., 2000). 11062540
3023 dgkA Neisseria meningitidis MC58 904121 15677409 NMB1558 NP_274565.1 diacylglycerol kinase Virulence factor MUTATION: dgkA mutant is attenuated in rats (Sun et al., 2000). 11062540
3024 purL from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904131 15677824 NMB1996 NP_274988.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Sun et al., 2000). 11062540
3025 NMB1966 Neisseria meningitidis MC58 904178 15677796 NMB1966 NP_274960.1 ABC transporter, ATP-binding protein Virulence factor MUTATION: NMB1966 mutant was less adhesive and invasive for human bronchial epithelial cells, had reduced survival in human blood and was attenuated in a systemic mouse model of infection (Li et al., 2009). 19050914
3026 ilvI from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904184 15677427 NMB1577 NP_274583.1 acetolactate synthase III, large subunit Virulence factor MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000). 11062540
3027 lgtA from Neisseria meningitidis MC58 Neisseria meningitidis MC58 904226 15677759 NMB1929 NP_274923.1 lacto-N-neotetraose biosynthesis glycosyl transferase LgtA Virulence factor MUTATION: lgtA mutant is attenuated in rats (Sun et al., 2000). 11062540
3888 ptsH from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221101 254804145 NMO_0123 YP_003082366.1 phosphocarrier protein HPr Virulence factor MUTATION: ptsH mutant is attenuated in rats (Sun et al., 2000). 11062540
3889 hrpA from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221120 254804179 NMO_0159 YP_003082400.1 ATP-dependent helicase Virulence factor MUTATION: hrpA mutant was deficient in the ability to grow/live in HeLa cells (Talà et al., 2008). 18680551
3890 purL from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221129 254804191 NMO_0171 YP_003082412.1 phosphoribosylformylglycinamidine synthase Virulence factor MUTATION: purL mutant is attenuated in rats (Sun et al., 2000). 11062540
3891 fhs from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221210 254804333 NMO_0323 YP_003082554.1 formate--tetrahydrofolate ligase Virulence factor MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000). 11062540
3892 aroB from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221238 254804371 NMO_0364 YP_003082592.1 3-dehydroquinate synthase Virulence factor MUTATION: aroB mutant is attenuated in rats (Sun et al., 2000). 11062540
3893 ilvD from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221600 254804977 NMO_1006 YP_003083198.1 dihydroxy-acid dehydratase Virulence factor MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000). 11062540
3894 exbD from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221908 254805476 NMO_1544 YP_003083697.1 biopolymer transport protein ExbD/TolR Virulence factor MUTATION: exbD mutant is attenuated in rats (Sun et al., 2000). 11062540
3895 nadA from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8221962 254805574 NMO_1648 YP_003083795.1 quinolinate synthetase A Virulence factor MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009). 19481311
3896 dedA from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222190 254804932 NMO_0955 YP_003083153.1 DedA protein Virulence factor MUTATION: dedA mutant is attenuated in rats (Sun et al., 2000). 11062540
3897 aroG from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222370 254805657 NMO_1733 YP_003083878.1 phospho-2-dehydro-3-deoxyheptonate aldolase Virulence factor MUTATION: aroG mutant is attenuated in rats (Sun et al., 2000). 11062540
3898 metG from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222414 254805891 NMO_1976 YP_003084112.1 Methionyl-tRNA synthetase Virulence factor MUTATION: metG mutant is attenuated in rats (Sun et al., 2000). 11062540
3899 aroE from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222416 254805606 NMO_1682 YP_003083827.1 Shikimate 5-dehydrogenase Virulence factor MUTATION: aroE mutant is attenuated in rats (Sun et al., 2000). 11062540
3900 lgtA from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222431 254804256 NMO_0241 YP_003082477.1 lacto-N-neotetraose biosynthesis glycosyl transferase Virulence factor MUTATION: lgtA mutant is attenuated in rats (Sun et al., 2000). 11062540
3901 ilvI from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222500 254805332 NMO_1388 YP_003083553.1 acetolactate synthase large subunit Virulence factor MUTATION: ilvI mutant is attenuated in rats (Sun et al., 2000). 11062540
3902 rfaK from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222536 254805454 NMO_1520 YP_003083675.1 alpha 1,2 N-acetylglucosamine transferase Virulence factor MUTATION: rfaK mutant is attenuated in rats (Sun et al., 2000). 11062540
3903 pilX Neisseria meningitidis alpha14 8222730 254804754 NMO_0766 YP_003082975.1 type IV pilus assembly protein Virulence factor MUTATION: pilX mutant had reduced adherence to human epithelial cells (Hélaine et al., 2005). 15612917
3904 ptsI from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222774 254804146 NMO_0124 YP_003082367.1 phosphoenolpyruvate-protein phosphotransferase Virulence factor MUTATION: ptsI mutant is attenuated in rats (Sun et al., 2000). 11062540
3905 pnp from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222779 254804638 NMO_0647 YP_003082859.1 polyribonucleotide nucleotidyltransferase Virulence factor MUTATION: pnp mutant is attenuated in rats (Sun et al., 2000). 11062540
3906 rfaE from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222793 254804701 NMO_0711 YP_003082922.1 ADP-heptose synthase Virulence factor MUTATION: rfaE mutant is attenuated in rats (Sun et al., 2000). 11062540
3907 aroD from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222803 254805227 NMO_1279 YP_003083448.1 3-dehydroquinate dehydratase Virulence factor MUTATION: aroD mutant is attenuated in rats (Sun et al., 2000). 11062540
3908 metF from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222872 254804826 NMO_0840 YP_003083047.1 5,10-methylenetetrahydrofolate reductase Virulence factor MUTATION: metF mutant is attenuated in rats (Sun et al., 2000). 11062540
3909 rfaF from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222929 254805293 NMO_1348 YP_003083514.1 ADP-heptose--LPS heptosyltransferase II Virulence factor MUTATION: rfaF mutant is attenuated in rats (Sun et al., 2000). 11062540
3910 aroC from Neisseria meningitidis alpha14 Neisseria meningitidis alpha14 8222977 254805436 NMO_1499 YP_003083657.1 Chorismate synthase Virulence factor MUTATION: aroC mutant is attenuated in rats (Sun et al., 2000). 11062540
4860 LOS Neisseria meningitidis Virulence factor MUTATION: Isolates with an immunotype other than L3,7,9 were less virulent in infant mouse model than N. menigitidis strains with the L2,7,9 LOS immunotype (Mackinnon et al., 1993).
7912406
4861 Polysaccharide capsule Neisseria meningitidis Virulence factor MUTATION: Non-groupable (acapsular) strains of N. meningitidis are avirulent in an infant mouse model of infection (Mackinnon et al., 1993).
7912406