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Found 12 gene(s). Export as Excel file, text file

Victors ID Gene Name Sequence Strain (Species/Organism) NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession Protein Name Molecule Role Molecule Role Annotation PMID
4525 UL41 Suid herpesvirus 1 2952522 51557510 SuHV1_gp27 S57917 YP_068344 tegument host shutoff protein Virulence factor MUTATION: A UL41 mutant is highly attenuated in mice (Lin et al., 2010).
20448414
4992 UL8.5 (gp50) Suid herpesvirus 1 2952548 51557533 SuHV1_gp50 BK001744 YP_068367 Virulence factor MUTATION: A gp50 null mutant is attenuated in pigs (Peeters et al., 1994). 8178562
4993 IE180 (gp63) Suid herpesvirus 1 2952540 51557548 SuHV1_gp63 BK001744 YP_068382 transcriptional regulator ICP4 Virulence factor MUTATION: A gp50+gp63 deletion mutant in Pseudorabies virus was attenuated in pigs (Peeters et al., 1994). 8178562
4994 glycoprotein E Suid herpesvirus 1 307634504 glycoprotein E Virulence factor MUTATION: gE mutant had strongly reduced virulence in pigs compared to wild-type PRV (Kimman et al., 1994).
MUTATION: A glycoprotein E mutant, in combination with UL23 and glycoprotein G mutations, is attenuated in raccoons (Weigel et al., 2003).
7975253 12488067
4995 glycoprotein G Suid herpesvirus 1 15422177 glycoprotein G Virulence factor MUTATION: A glycoprotein G mutant, in combination with UL23 and glycoprotein E mutations, is attenuated in raccoons (Weigel et al., 2003). 12488067
4996 glycoprotein M Suid herpesvirus 1 strain Kaplan 1478255 UL10 Virulence factor MUTATION: A glycoprotein M, gM, deletion in pseudorabies virus was attenuated in piglets (Dijkstra et al., 1997). 9292000
4997 UL23 Suid herpesvirus 1 2952559 51557518 SuHV1_gp35 BK001744 YP_068352 thymidine kinase Virulence factor MUTATION: a thymidine kinase PRV mutant is attenuated in pigs (Kimman et al., 1994).
MUTATION: A UL23 mutant, in combination with mutations in glycoproteins G and E, is attenuated in raccoons (Weigel et al., 2003).
7975253 12488067
4998 UL50 Suid herpesvirus 1 2952537 51557490 SuHV1_gp07 BK001744 YP_068324 deoxyuridine triphosphatase Virulence factor MUTATION: A UL50 mutant is attenuated in pigs (Jöns et al., 1997). 9228681
4999 US3 Suid herpesvirus 1 2952561 126802155 SuHV1_gp65 BK001744 YP_068384 serine/threonine protein kinase US3 Virulence factor MUTATION: US3 mutant is attenuated in pigs (Kimman et al., 1994). 7975253
5025 UL21 Suid herpesvirus 1 2952541 51557520 SuHV1_gp37 BK001744 YP_068354 tegument protein UL21 Virulence factor Mutant UL21 was constructed by insertion of an oligonucleotide that contains stop codons, In two PRV mutants carrying the oligonucleotide at two sites within UL21, processing of newly replicated viral DNA was impaired. The results show that one of the UL21 mutants has strongly reduced virulence for mice. (de et al., 1992)
1331512
5032 US8 Suid herpesvirus 1 2952517 51557555 SuHV1_gp70 AY368490 YP_068389 envelope glycoprotein E Virulence factor Pigs immunized with M30, lacked amino acids valine (125) and cysteine(126) in an immunodominant antigenic region of glycoprotein I, were completely protected against challenge infection; no clinical signs of disease were detected, no virus was shed, and no secondary antibody response was detected. (Jacobs et al., 1993) 8409943
5077 US9 Suid herpesvirus 1 2952552 51557556 SuHV1_gp71 JF797219 YP_068390 membrane protein US9 Virulence factor Viruses with Us9 deleted have no observable defects in tissue culture yet have reduced virulence and restricted spread to retinorecipient neurons in the rodent brain.
(Brideau et al., 2000)
10775591