Border Color Location
  Extracellular
  Cell membrane
  Cytoplasm
  Organelle
  Bacterial membrane or virus envelope
  Other
Backgound Color Node Shape Object Type
  Box Protein or gene
  Box Protein of gene complex
  Ellipse Pathway or action
  Box Eukaryotic cell or cell component
  Box Microorganism or its component
  Box Microbe-host cell complex

Phinet Name: Bacillus anthracis

Phinet Information
Pathogen Name: Bacillus anthracis
Pathogen NIAID Category: NIAID Category A
Bio-objects
Bio-object 1: Acidified Phagolysosome
  • Type: Eukaryotic cell or cell component
  • Location: Cytoplasm
Bio-object 2: Apoptosis
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Unknown
Bio-object 3: ATP
  • Type: Protein or gene
  • Location: Cytoplasm
  • Function: Motor
Bio-object 4: ATR
  • Type: Protein or gene
  • Location: Cell membrane
  • Function: Ligand binding or carrier
Bio-object 5: Ca2+ Influx
  • Type: Other -- ion
  • Location: Cytoplasm
  • Function: Signal transducer
Bio-object 6: Calmodulin
  • Type: Protein or gene
  • Location: Cytoplasm
  • Function: Signal transducer
Bio-object 7: Calmodulin + active(EF+Mg2+ATP)
  • Type: Protein or gene complex
  • Location: Cytoplasm
Bio-object 8: Calmodulin + EF(active)
  • Type: Protein or gene complex
  • Location: Cytoplasm
  • Function: Signal transducer
Bio-object 9: Cytokine expression suppressed
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Defense, immunity protein
Bio-object 10: Edema Factor
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 11: Endosome containing Toxin complex
  • Type: Eukaryotic cell or cell component
  • Location: Cytoplasm
Bio-object 12: Free Edema Factor(inactive)
  • Type: Protein or gene
  • Location: Cytoplasm
  • Function: Enzyme
Bio-object 13: Free Lethal Factor
  • Type: Protein or gene
  • Location: Cytoplasm
  • Function: Enzyme
Bio-object 14: Furin
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 15: Furin
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 16: H+
  • Type: Other -- ion
  • Location: Cytoplasm
  • Function: Signal transducer
Bio-object 17: Increased cyclicAMP
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Signal transducer
Bio-object 18: Interleukin6 expression suppressed
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Defense, immunity protein
Bio-object 19: Lethal Factor
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 20: Lysosome
  • Type: Eukaryotic cell or cell component
  • Location: Cytoplasm
Bio-object 21: Macrophage Cell Surface
  • Type: Eukaryotic cell or cell component
  • Location: Cell membrane
Bio-object 22: MAPKK
  • Type: Protein or gene
  • Location: Cytoplasm
  • Function: Enzyme
Bio-object 23: MAPKK degraded
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Enzyme
Bio-object 24: Mg2+
  • Type: Other -- ion
  • Location: Cytoplasm
Bio-object 25: NF-kappa-B repression
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Transcription regulation
Bio-object 26: Phagolysosome
  • Type: Eukaryotic cell or cell component
  • Location: Cytoplasm
Bio-object 27: Protective Antigen(63) (6 molecules)
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 28: Protective Antigen(63) + ATR
  • Type: Protein or gene complex
  • Location: Extracellular
  • Function: Enzyme
Bio-object 29: Protective Antigen(63)-Heptamer + ATR (7 Molecules)
  • Type: Protein or gene complex
  • Location: Extracellular
  • Function: Enzyme
Bio-object 30: Protective Antigen(63)-Heptamer + ATR (7 Molecules) + LF / EF
  • Type: Protein or gene complex
  • Location: Extracellular
  • Function: Enzyme
Bio-object 31: Protective Antigen(86)
  • Type: Protein or gene
  • Location: Extracellular
  • Function: Enzyme
Bio-object 32: Protective Antigen(86) + ATR
  • Type: Protein or gene complex
  • Location: Extracellular
  • Function: Enzyme
Bio-object 33: Protective Antigen(86) + ATR + Furin
  • Type: Protein or gene complex
  • Location: Extracellular
  • Function: Enzyme
Bio-object 34: TNF alpha expression suppressed
  • Type: Pathway or action
  • Location: Cytoplasm
  • Function: Defense, immunity protein
Interactions
Interaction 1: Interaction1
Interaction 2: Interaction2
Interaction 3: Interaction3
Interaction 4: Interaction4
Interaction 5: Interaction5
Interaction 6: Interaction6
Interaction 7: Interaction7
Interaction 8: Interaction8
Interaction 9: Interaction9
Interaction 10: Interaction10
Interaction 11: Interaction11
Interaction 12: Interaction12
Interaction 13: Interaction12-1
Interaction 14: Interaction13
Interaction 15: Interaction14
Interaction 16: Interaction15
Interaction 17: Interaction15-1
Interaction 18: Interaction16
Interaction 19: Interaction17
Interaction 20: Interaction18
Interaction 21: Interaction19
Pathways