Phinet Name: Bacillus anthracis
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| Phinet Information |
| Pathogen Name:
Bacillus anthracis |
| Pathogen NIAID Category:
NIAID Category A |
| Bio-objects |
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Bio-object 1: Acidified Phagolysosome
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- Type: Eukaryotic cell or cell component
- Location: Cytoplasm
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Bio-object 2: Apoptosis
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Unknown
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Bio-object 3: ATP
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- Type: Protein or gene
- Location: Cytoplasm
- Function: Motor
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Bio-object 4: ATR
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- Type: Protein or gene
- Location: Cell membrane
- Function: Ligand binding or carrier
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Bio-object 5: Ca2+ Influx
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- Type: Other -- ion
- Location: Cytoplasm
- Function: Signal transducer
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Bio-object 6: Calmodulin
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- Type: Protein or gene
- Location: Cytoplasm
- Function: Signal transducer
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Bio-object 7: Calmodulin + active(EF+Mg2+ATP)
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- Type: Protein or gene complex
- Location: Cytoplasm
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Bio-object 8: Calmodulin + EF(active)
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- Type: Protein or gene complex
- Location: Cytoplasm
- Function: Signal transducer
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Bio-object 9: Cytokine expression suppressed
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Defense, immunity protein
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Bio-object 10: Edema Factor
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 11: Endosome containing Toxin complex
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- Type: Eukaryotic cell or cell component
- Location: Cytoplasm
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Bio-object 12: Free Edema Factor(inactive)
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- Type: Protein or gene
- Location: Cytoplasm
- Function: Enzyme
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Bio-object 13: Free Lethal Factor
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- Type: Protein or gene
- Location: Cytoplasm
- Function: Enzyme
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Bio-object 14: Furin
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 15: Furin
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 16: H+
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- Type: Other -- ion
- Location: Cytoplasm
- Function: Signal transducer
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Bio-object 17: Increased cyclicAMP
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Signal transducer
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Bio-object 18: Interleukin6 expression suppressed
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Defense, immunity protein
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Bio-object 19: Lethal Factor
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 20: Lysosome
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- Type: Eukaryotic cell or cell component
- Location: Cytoplasm
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Bio-object 21: Macrophage Cell Surface
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- Type: Eukaryotic cell or cell component
- Location: Cell membrane
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Bio-object 22: MAPKK
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- Type: Protein or gene
- Location: Cytoplasm
- Function: Enzyme
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Bio-object 23: MAPKK degraded
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Enzyme
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Bio-object 24: Mg2+
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- Type: Other -- ion
- Location: Cytoplasm
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Bio-object 25: NF-kappa-B repression
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Transcription regulation
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Bio-object 26: Phagolysosome
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- Type: Eukaryotic cell or cell component
- Location: Cytoplasm
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Bio-object 27: Protective Antigen(63) (6 molecules)
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 28: Protective Antigen(63) + ATR
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- Type: Protein or gene complex
- Location: Extracellular
- Function: Enzyme
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Bio-object 29: Protective Antigen(63)-Heptamer + ATR (7 Molecules)
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- Type: Protein or gene complex
- Location: Extracellular
- Function: Enzyme
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Bio-object 30: Protective Antigen(63)-Heptamer + ATR (7 Molecules) + LF / EF
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- Type: Protein or gene complex
- Location: Extracellular
- Function: Enzyme
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Bio-object 31: Protective Antigen(86)
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- Type: Protein or gene
- Location: Extracellular
- Function: Enzyme
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Bio-object 32: Protective Antigen(86) + ATR
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- Type: Protein or gene complex
- Location: Extracellular
- Function: Enzyme
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Bio-object 33: Protective Antigen(86) + ATR + Furin
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- Type: Protein or gene complex
- Location: Extracellular
- Function: Enzyme
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Bio-object 34: TNF alpha expression suppressed
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- Type: Pathway or action
- Location: Cytoplasm
- Function: Defense, immunity protein
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| Interactions |
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Interaction 1: Interaction1 |
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Interaction 2: Interaction2 |
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Interaction 3: Interaction3 |
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Interaction 4: Interaction4 |
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Interaction 5: Interaction5 |
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Interaction 6: Interaction6 |
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Interaction 7: Interaction7 |
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Interaction 8: Interaction8 |
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Interaction 9: Interaction9 |
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Interaction 10: Interaction10 |
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Interaction 11: Interaction11 |
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Interaction 12: Interaction12 |
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Interaction 13: Interaction12-1 |
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Interaction 14: Interaction13 |
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Interaction 15: Interaction14 |
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Interaction 16: Interaction15 |
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Interaction 17: Interaction15-1 |
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Interaction 18: Interaction16 |
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Interaction 19: Interaction17 |
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Interaction 20: Interaction18 |
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Interaction 21: Interaction19 |
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| Pathways |